Results 71 to 80 of about 6,125,574 (326)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Promoting Improved Access to Consumer Health Information [PDF]

open access: yes, 2005
“Do you have any information on lupus?” “What are the side effects of Prozac?” “I want to find an herbal remedy for arthritis.” Questions such as these are asked each day across the country at public library reference desks.
Kaiser, Josephine
core  

Mobile Wellness Resources [PDF]

open access: yes, 2016
Stress in medical students is not unheard of, nor is it unexpected. Medical students have rigorous schedules and must pass a series of examinations, placing enormous pressure on them to succeed.
Herron, Jennifer
core   +1 more source

Hello World Deep Learning in Medical Imaging

open access: yesJournal of digital imaging, 2018
There is recent popularity in applying machine learning to medical imaging, notably deep learning, which has achieved state-of-the-art performance in image analysis and processing. The rapid adoption of deep learning may be attributed to the availability
P. Lakhani   +4 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Krankenhausbibliotheken, Pharmabibliotheken, veterinärmedizinische Bibliotheken / Hospital libraries, pharmaceutical libraries, veterinary medical libraries

open access: yesGMS Medizin – Bibliothek – Information, 2011
The recent issue 1-2/2011 of GMS Medizin – Bibliothek – Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, Bruno
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Elektronik Sağlık Kayıt Sistemlerinin Kütüphanelerle Bütünleştirilmesi / Integrating Libraries to Electronic Health Record Systems

open access: yesBilgi Dünyası, 2005
The increase of volume and variety of information, which in turn has an important role in health services, reached to an explosive bulk, that can hardly be managable for the users.
Ayşen Küyük   +2 more
doaj  

GPU acceleration for statistical gene classification [PDF]

open access: yes, 2010
The use of Bioinformatic tools in routine clinical diagnostics is still facing a number of issues. The more complex and advanced bioinformatic tools become, the more performance is required by the computing platforms.
Benso, Alfredo   +3 more
core   +1 more source

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