Results 111 to 120 of about 4,394,525 (348)

DNA-Encoded Chemical Libraries: Achievements and Remaining Challenges

FEBS Letters, 2018
DNA‐encoded chemical libraries (DECLs) are collections of compounds, individually coupled to DNA tags serving as amplifiable identification barcodes. Since individual compounds can be identified by the associated DNA tag, they can be stored as a mixture,
N. Favalli, G. Bassi, Jörg Scheuermann, D. Neri   +3 more
semanticscholar   +1 more source

The Implementation of Keenious at Carnegie Mellon University

Journal of eScience Librarianship
In the fall of 2022, the Carnegie Mellon University (CMU) Libraries began investigating Keenious—an artificial intelligence (AI)-based article recommender tool—for a possible trial implementation to improve pathways to resource discovery and assist ...
Ashley Werlinich, Dom Jebbia, Joelen Pastva, Maranda Reilly   +3 more
doaj   +2 more sources

The Consortium of European Research Libraries (CERL): twenty years of promoting Europe’s cultural heritage in print and manuscript

027.7, 2014
The Consortium of European Research Libraries (CERL, http://www.cerl.org) is a membership organisation, involving an active community of c. 190 libraries each with a keen focus on cultural heritage in the form of early printed books and manuscripts ...
Ingeborg Versprille, Marian Lefferts, Cristina Dondi   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

LibQual+ Lite Spring 2008 Survey: University of North Texas Libraries

, 2008
This report contains information from the Spring 2008 pilot administration of the LibQUAL+® Lite protocol at University of North Texas Libraries. The goal of LibQUAL+® Lite is to measure user satisfaction in the same valid matter as the original LibQUAL+®
Association of Research Libraries
core  

Modeling the expansion of virtual screening libraries

Nature Chemical Biology, 2023
Jiankun Lyu, J. Irwin, B. Shoichet
semanticscholar   +1 more source

Asset Mapping at Halifax Public Libraries: A Tool for Beginning to Discover the Library’s Role with the Immigrant Community in Halifax

Partnership: The Canadian Journal of Library and Information Practice and Research, 2012
As library systems across Canada begin to grapple with the implications community-led service planning has on program and service development, new tools are being developed to assist library staff.
Kenneth William Williment, Tracey Jones-Grant   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Semantic Web Technologies for Digital Libraries: From Libraries to Social Semantic Digital Libraries (SSDL), Over Semantic Digital Libraries (SDL)

, 2010
Digital libraries have been an important source of information throughout the history of mankind. It has been present in our societies in different forms. Notably, traditional libraries have found their on the desktops of internet users.
Alotaibi, Sara
core  

Personalisation and recommender systems in digital libraries [PDF]

, 2005
Widespread use of the Internet has resulted in digital libraries that are increasingly used by diverse communities of users for diverse purposes and in which sharing and collaboration have become important social elements.
Smeaton, Alan F., Callan, Jamie
core   +1 more source