Results 111 to 120 of about 2,190,696 (310)

Special Libraries, March 1936 [PDF]

, 1936
Volume 27, Issue 3https://scholarworks.sjsu.edu/sla_sl_1936/1002/thumbnail ...
Special Libraries Association
core   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Special Libraries, May-June 1952 [PDF]

, 1952
Volume 43, Issue 5https://scholarworks.sjsu.edu/sla_sl_1952/1004/thumbnail ...
Special Libraries Association
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Special Libraries, February 1912 [PDF]

, 1912
Volume 3, Issue 2https://scholarworks.sjsu.edu/sla_sl_1912/1001/thumbnail ...
Special Libraries Association
core   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Library-to-library screening [PDF]

Nature Biotechnology, 1999
openaire   +2 more sources

Special Libraries, October 1934 [PDF]

, 1934
Volume 25, Issue 8https://scholarworks.sjsu.edu/sla_sl_1934/1007/thumbnail ...
Special Libraries Association
core   +2 more sources

Special Libraries, May-June 1943 [PDF]

, 1943
Volume 34, Issue 5https://scholarworks.sjsu.edu/sla_sl_1943/1004/thumbnail ...
Special Libraries Association
core   +1 more source