Results 91 to 100 of about 786,736 (344)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Author productivity analysis in Q1 of authors in journal library and information science Q1 journals using with Lotka’s Law

Berkala Ilmu Perpustakaan dan Informasi
Introduction. The purpose of this study is to use Lotka's law to determine the pattern of author output in the field of Library Science in the Library Science Journal Q1 indexed by Scopus. Data Collection Methods.
Nasya Meilia Pratiwi, Cecep Ibrahim, Nisya Ula Alkarimah, Zalika Naila Arifah, Thufailah Hamida Jatmik, Afini Mutiara, Amelia Fatimah Azzahra, Sherin Wiryani Putri, Danang Dwijo Kangko, Rina Astarika, Jopang Jopang   +10 more
doaj   +1 more source

Library and Information Science education: look beyond library and information services

Sri Lankan Journal of Librarianship and Information Management, 2009
Development of librarianship, though has good theoretical support, is not emulated to the sciences and art of knowledge society. Librarianship, as a profession, emanated through accumulation of ideas from various professionals entities. However due to the varied needs of the users, technological application, derivation of information activity in ...
HS Siddamallaiah, CR Karisiddappa
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Open access journals in the field of library and information sciences (LIS)

, 2023
Volkova Irina
openalex   +1 more source

Research on Visualization of international research Cooperation Results in China Library and Information Science based on Big Data [PDF]

, 2023
Duanwu Yan, Chenhe Yang, Qiaoyu Chen
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

From Crisis to Transformation: Lessons Learned and Recommendations for LIS Graduate Programs in Thailand Post-Pandemic

Journal of Information Science Theory and Practice
This study aims to investigate the management of library and information science (LIS) graduate programs in Thailand during the COVID-19 pandemic and highlights the challenges faced by the programs’ chairs, faculty members, and graduate students during ...
Sujira Ammarukleart, Chutima Sacchanand, Nilobon Wimolsittichai, Duangkaew Ngernpoolsap, Jutatip Chanlun   +4 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source