Results 21 to 30 of about 713,296 (247)
Library and Information Science (LIS) Transferable Competencies
Partnership: The Canadian Journal of Library and Information Practice and Research, 2013 This article uses data obtained from a content analysis of job advertisements to explore the questions of (1) what types of non-traditional jobs are available for library and information science (LIS) professionals and (2) how can LIS students and ...
Melissa Fraser-Arnott
doaj +1 more source
Performance of Search Engines and Specialized Medical Databases in the Field of Cancer
مدیریت اطلاعات سلامت, 2021 Introduction: Seeng as web has become an important source of information and search vehicle to retrieve information on the web, it is important to identify the capabilities and limitations of these tools.
Leila Nemati-Anaraki +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Survey Study Marketing Process in the University Libraries of Isfahan City Based on 7P [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2013 Objective: the aim of this study is to determine the improvement rate of marketing process based on 7P in Libraries of state universities in Isfahan city.Method: This research is a descriptive – survey study.
Ahmad Shabani +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Lentera Pustaka: Jurnal Kajian Ilmu Perpustakaan, Informasi dan KearsipanMahasiswa Universitas Padjadjaran (Unpad) membutuhkan informasi sebagai penunjang perkuliahannya, untuk itu mereka melakukan pencarian informasi. Salah satu sumber informasi adalah Perpustakaan Pusat yang dikenal sebagai Kandaga, yang menyediakan ...
Saleha Rodiah +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source