Results 31 to 40 of about 3,025,022 (290)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Review of wide band-gap semiconductors technology

open access: yesMATEC Web of Conferences, 2016
Silicon carbide (SiC) and gallium nitride (GaN) are typical representative of the wide band-gap semiconductor material, which is also known as third-generation semiconductor materials.
Jin Haiwei   +4 more
doaj   +1 more source

Implications for Library and Information Science Education [PDF]

open access: yes, 1984
published or submitted for ...
Lancaster, F.W.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Library and Information Science (LIS) Transferable Competencies

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research, 2013
This article uses data obtained from a content analysis of job advertisements to explore the questions of (1) what types of non-traditional jobs are available for library and information science (LIS) professionals and (2) how can LIS students and ...
Melissa Fraser-Arnott
doaj   +1 more source

Performance of Search Engines and Specialized Medical Databases in the Field of Cancer

open access: yesمدیریت اطلاعات سلامت, 2021
Introduction: Seeng as web has become an important source of information and search vehicle to retrieve information on the web, it is important to identify the capabilities and limitations of these tools.
Leila Nemati-Anaraki   +2 more
doaj   +1 more source

Library and information science publishing : global open access [PDF]

open access: yes, 2005
Brief article describing E-LIS, an open access repository for library and information science material in a range of formats and languages. E-LIS was set up in 2003 with initial funding from the Spanish Ministry of Education, Culture and Sports, in line ...
Brown, Kristina, McCulloch, Emma
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Survey Study Marketing Process in the University Libraries of Isfahan City Based on 7P [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2013
Objective: the aim of this study is to determine the improvement rate of marketing process based on 7P in Libraries of state universities in Isfahan city.Method: This research is a descriptive – survey study.
Ahmad Shabani   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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