Results 21 to 30 of about 823,276 (296)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
LCSH and PRECIS in library and information science : a comparative study [PDF]
, 1992 Made available in DSpace on 2008-03-15T16:30:16Z (GMT). No. of bitstreams: 3 gslisoccasionalpv00000i00194.pdf: 3545205 bytes, checksum: 9af38d944a3c553d6d4647addf04a8d5 (MD5) gslisoccasionalpv00000i00194_ocr.txt: 149929 bytes, checksum ...
Tonta, Yasar Ahmet, Tonta, Yaşar
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Needs and challenges with respect to establishing a collaboratory within library and information science: Practioners' perspectives [PDF]
, 2006 This paper reports on a study that explored the needs and challenges with respect to the creation of a collaboratory for library and information science practitioners.
Sonnenwald, Diane H. +6 more
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A Survey Study Marketing Process in the University Libraries of Isfahan City Based on 7P [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2013 Objective: the aim of this study is to determine the improvement rate of marketing process based on 7P in Libraries of state universities in Isfahan city.Method: This research is a descriptive – survey study.
Ahmad Shabani +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Lentera Pustaka: Jurnal Kajian Ilmu Perpustakaan, Informasi dan KearsipanMahasiswa Universitas Padjadjaran (Unpad) membutuhkan informasi sebagai penunjang perkuliahannya, untuk itu mereka melakukan pencarian informasi. Salah satu sumber informasi adalah Perpustakaan Pusat yang dikenal sebagai Kandaga, yang menyediakan ...
Saleha Rodiah +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source