Results 101 to 110 of about 513,578 (251)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

A Research on Tabriz University of Medical Sciences Libraries Staff, Collection, Space and Budget Comparison with Iranian University Libraries Standards

مدیریت اطلاعات سلامت, 2010
Introduction: Academic libraries are famous to be the hearts of universities, with the ever increasing importance of the evaluation of information technologies in academic centers, and libraries need to evaluate their status to accord with these ...
Kamal Ebrahimi, Shafi Habibi, Gholamhossein Tasbihi   +2 more
doaj  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Evaluating the Knowledge of Physicians about and their Usage of Iranian National Medical Digital Library in Isfahan University of Medical Sciences, Iran

مدیریت اطلاعات سلامت, 2012
• Introduction: Increasing volume of information in various sciences, such as medicine, has led to the use of various strategies to effectively provide students, researchers, and teachers with medical and paramedical information.
Shahin Mojiri, Alireza Rahimi, Zahra Bahrami, Mohsen Yaghoubi, Parvin Hematian   +4 more
doaj  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Collaboration Rate among Researchers in Research Center of IUMS in Carrying out Research Projects

مدیریت اطلاعات سلامت, 2009
Introduction: We face with the globalization and increasing development of communication in all aspects nowadays. As a result researchers and specialists should proceed to more communication and scientific collaboration and co- authorship, because ...
Farshid Danesh, Amir Hossein Abdulmajid, Alireza Rahimi, Fatemeh Babaie   +3 more
doaj  

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

مقایسه‌ی سواد اطلاعاتی دانشجویان پزشکی دانشگاه علوم پزشکی اصفهان با استاندارد قابلیت‌های سواد اطلاعاتی برای آموزش عالی

مدیریت اطلاعات سلامت, 2013
مقدمه: «استاندارد قابلیت‌های سواد اطلاعاتی برای آموزش عالی» بر تعیین و تشخیص ماهیت و گستره‌ی اطلاعات مورد نیاز، دسترسی به اطلاعات، ارزیابی اطلاعات، استفاده‌ی مؤثر از اطلاعات و درک مسایل اقتصادی و حقوقی- اجتماعی مربوط به استفاده از اطلاعات تأکید دارد.
Mohammadreza Hashemian, Mohammadjavad Alemokhtar, Akbar Hasanzadeh   +2 more
doaj