Results 81 to 90 of about 513,578 (251)
مدیریت اطلاعات سلامت, 2017 Introduction: Scholars of different fields need open-access and subscribed electronic resources to access scientific information. However, with the increasing growth of electronic resources and the replacement of printed materials with digital ...
Sayed Javad Ghazi-Mirsaeed +2 more
doaj
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Common data quality elements for health information systems: a systematic review
BMC Medical Informatics and Decision MakingBackground Data quality in health information systems has a complex structure and consists of several dimensions. This research conducted for identify Common data quality elements for health information systems.
Hossein Ghalavand +4 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Scientometric Study and Visualization of Multiple Sclerosis-Related Publications during 1999-2008
مدیریت اطلاعات سلامت, 2011 Introduction: The purpose of this study was to visualize the scientific structure of multiple sclerosis (MS) during 1999-2008 and to use scientometric indicators for analysis of MS-related scientific publications indexed in Web of Science Database ...
Afshin Hamdipour, Farideh Osareh
doaj
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
TASK Quarterly, 2017 The types of natural and agricultural science resources contained in the AGRO database have been characterized and their dynamic development in qualitative and quantitative terms in 2009–2016 has been described.
ZOFIA KASPRZAK +2 more
doaj
The Place of Library Science and Information-Documentation Science in Information Science
, 1973 (The author) is German and is now considered one of the leading international scholars and specialists in information science. After being developed and transformed into the "Institute of Scientific Librarianship and Information" in 1966, the Institute of Librarianship at Humboldt University-Berlin organized a colloquium entitled "The Subject and ...
openaire +2 more sources
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source