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The Effects of Information Technologies on Using Reference Services: from the Viewpoint of Reference Librarians of Iran Universities

open access: yesمدیریت اطلاعات سلامت, 2012
• Introduction: The reference section is one of the most important parts in every library. Moreover, reference services represent all the attempts performed in a library. Since libraries primarily aim to satisfy users' information needs, knowing that the
Sadigheh Raeisi   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Knowledge management in libraries and information centers: theory and practice

open access: yesCybrarians Journal, 2009
Library and information professionals face the challenge of improving and expanding networks for sharing knowledge and expertise gained over many years of experience and collection.
Fahd Al Duwayhi
doaj   +1 more source

Documentation, information science, and library science in the U.S.A. [PDF]

open access: yesInformation Processing & Management, 1996
Abstract Three related questions are addressed: why was the work of the European documentalists largely ignored in the U.S.A. before the Second World War? What was the “information science vs library science” argument about? Technological innovation was a vital force in library science in the late 19th century and again after 1950.
openaire   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Health Information Seeking Behavior among the Users of Public Libraries in Isfahan City, Iran

open access: yesمدیریت اطلاعات سلامت, 2019
Introduction: Investigating the health information seeking behavior of users can help librarians to provide appropriate services, and help public libraries to make effective decisions and plans.
Nasrin Musarezai   +2 more
doaj   +1 more source

The whiteness of European Library and Information Science

open access: yesEducation for Information, 2023
This paper studies the state of discussions on DE&I and racism within LIS in EU higher education institutions.
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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