Results 51 to 60 of about 513,578 (251)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Empowering community at Kampung 1001 Malam through website development

open access: yesJournal of Community Service and Empowerment
In the age of information technology, website development has become a crucial solution in empowering communities, and this article highlights the important role that library and information science students play in this endeavour.
Ragil Tri Atmi   +6 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

هزینه- سودمندی کتاب‌های فارسی مربوط به رشته‌ی کتابداری و اطلاع‌رسانی در دانشگاه علوم پزشکی جندی شاپور اهواز

open access: yesمدیریت اطلاعات سلامت, 2012
مقدمه: ارزیابی‌های کمی از معیارهای مناسب جهت تأیید یا رد انتخاب منابع اطلاعاتی کتابخانه‌ها به شمار می‌روند. از طریق این ارزیابی‌ها می‌توان تناسب بین منابع انتخاب شده با نیازهای جامعه‌ی استفاده کننده‌ی کتابخانه را با توجه به میزان استفاده‌ی آنان از منابع ...
Firoozeh Zare Farashbandi   +3 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

A Comparative Study on the Central Library Websites of Iranian State Universities in HTML and Dublin Core Metadata Element Usage

open access: yesمدیریت اطلاعات سلامت, 2013
Introduction: Recent progress in providing innovative solutions in the organization of electronic resources and research in this area shows the global trend in the use of new strategies such as metadata to facilitate descripting, locating, organizing ...
Mahtab Ramezan Shirazi   +3 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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