There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
Correction: Evaluating the associations and predictive performance of triglyceride-glucose index and related indicators for chronic diseases in a Chinese cohort. [PDF]
PLOS One Staff.
europepmc +1 more source
THE IMPORTANCE OF LIBRARY ASSOCIATIONS: WHY AND HOW IAMSLIC ADDS VALUE TO YOUR LIBRARY: SPC PERSPECTIVE [PDF]
Nakalevu, Samuela
core
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
Echoes in the Deep: Revealing Influenza A Viruses' Persistence and Microbial Associations in Aquatic Ecosystems. [PDF]
Chen W +16 more
europepmc +1 more source
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang +9 more
wiley +1 more source
Cognitive Networks for Knowledge Modeling: A Gentle Introduction for Data- and Cognitive Scientists. [PDF]
Haim E, Stella M.
europepmc +1 more source
Chemoselective Sequential Polymerization: An Approach Toward Mixed Plastic Waste Recycling
Inspired by biological protein metabolism, this study demonstrates the closed‐loop recycling of mixed synthetic polymers via ring‐closing depolymerization followed by a chemoselective sequential polymerizations process. The approach recovers pure polymers from mixed feedstocks, even in multilayer formats, highlighting a promising strategy to overcome a
Gadi Slor +5 more
wiley +1 more source
Oral Health Determinants of Frailty in Older Adults: An Umbrella Review of Systematic Reviews and Meta-Analyses. [PDF]
Lokman N, Nayan NAM, Choong EKM.
europepmc +1 more source

