Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
A national benchmarking survey to explore the use of dose error reduction software in adult intensive care units (ICUs). [PDF]
Morgan S, Lamont S.
europepmc +1 more source
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Associations between maternal prepregnancy body mass index and maternal and cord blood metabolome. [PDF]
Sormunen-Harju H +9 more
europepmc +1 more source
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source
Joint modeling of longitudinal biomarker and survival outcomes with the presence of competing risk in the nested case-control studies with application to the TEDDY microbiome dataset. [PDF]
Zhao Y +7 more
europepmc +1 more source
13 Library Associations, Library Management, Library Staff and Library Advocacy
openaire +1 more source
Cephalopod‐inspired photonic microparticles with dynamic structural coloration are fabricated via confined self‐assembly of linear block copolymers into ellipsoids containing stacked lamellae. Embedded superparamagnetic nanoparticles enable rapid magnetic alignment, restoring vivid, angle‐dependent color.
Gianluca Mazzotta +8 more
wiley +1 more source
Beyond the bowel: novel comorbidity patterns in inflammatory bowel disease from the all of us research program. [PDF]
Sudhakaran SC +5 more
europepmc +1 more source

