Results 31 to 40 of about 1,348,933 (298)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Kontekstualisasi pemikiran S. R. Ranganathan dalam perkembangan dunia perpustakaan masa kini

open access: yesPustaka Karya: Jurnal Ilmiah Ilmu Perpustakaan dan Informasi, 2023
Science is dynamic so it continues to develop over time. A number of figures contributed to coloring scientific dynamics, one of which was S.R Ranganathan who dedicated his life to the world of libraries. His name is well known as the Father of Libraries
Husna Amalina Sholihah   +2 more
doaj   +1 more source

Two-dimensional ranking of Wikipedia articles

open access: yes, 2010
The Library of Babel, described by Jorge Luis Borges, stores an enormous amount of information. The Library exists {\it ab aeterno}. Wikipedia, a free online encyclopaedia, becomes a modern analogue of such a Library. Information retrieval and ranking of
A. Capocci   +15 more
core   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A comme Alphabet, B comme Bibliothèque, C comme Clément…

open access: yesStrenae, 2010
In this article, Corinne Gibello-Bernette, librarian in the Literature and Art Department at the Centre national du livre pour la jeunesse—La Joie par les livres, details the Clément classification system.
Corinne Gibello-Bernette
doaj   +1 more source

Survey of Web Developers in Academic Libraries [PDF]

open access: yes, 2008
A survey was sent to library web designers from randomly selected institutions to determine the background, tools, and methods used by those designers. Results, grouped by Carnegie Classification type, indicated that larger schools were not necessarily ...
Connell, Ruth S
core   +2 more sources

Musical instrument mapping design with Echo State Networks [PDF]

open access: yes, 2014
Echo State Networks (ESNs), a form of recurrent neural network developed in the field of Reservoir Computing, show significant potential for use as a tool in the design of mappings for digital musical instruments.
Kiefer, Chris
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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