Results 41 to 50 of about 52,574 (296)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Modular, robust, and extendible multicellular circuit design in yeast

open access: yeseLife, 2022
Division of labor between cells is ubiquitous in biology but the use of multicellular consortia for engineering applications is only beginning to be explored. A significant advantage of multicellular circuits is their potential to be modular with respect
Alberto Carignano   +5 more
doaj   +1 more source

Library purchasing consortia: their activity and effect on the marketplace [PDF]

open access: yes, 2000
This chapter is based on a survey undertaken for a BLRIC/LIC-funded research project (RIC/G/403). It describes the models of operation of purchasing consortia in three library sectors (health, higher education and public libraries) and discusses present
Ball, David, Pye, Jo
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Libraries and licencing

open access: yesKnjižnica, 2001
In the mid 90s, the abundance of various electronic publications exposed libraries to the problems of licensing electronic content. Various licensing principles have been prepared recently to help libraries in the process; it can be said that in general,
Maja Žumer
doaj   +1 more source

Library purchasing consortia in the UK: activity and practice [PDF]

open access: yes, 1999
This Briefing is based on a survey undertaken for a BLRIC/LIC-funded research project (RIC/G/403). It describes the models of operation of purchasing consortia in four library sectors (further education, health, higher education and public libraries ...
Ball, David, Pye, Jo
core  

Procuring electronic information: new business models in the context of the supply chain [PDF]

open access: yes, 2000
Examines the information value chain and some of its concepts, first for printed information and second for electronic information. Discusses the procurement process and, in the light of the analysis made earlier in the paper, evaluates the various ...
Ball, David, Wright, Susan
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Supporting Library Consortia Website Needs: Two Case Studies

open access: yesCode4Lib Journal, 2023
LOUIS: The Louisiana Library Network provides library technology infrastructure, electronic resources, affordable learning, and digital literacy support for its 47 academic library members.
Elizabeth Joan Kelly
doaj  

“Playing Well With Others”: New Opportunities for Library Consortia

open access: yesTheological Librarianship, 2012
Libraries everywhere are facing a complex array of budget cuts, staff retirements, technological disruption, etc. Many libraries may feel that they do not possess the organizational strength they once enjoyed, and as a result, an increasing number are ...
James Wiser
doaj   +1 more source

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