Results 131 to 140 of about 368,010 (306)

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu   +15 more
wiley   +1 more source

Protecting Library Patron Privacy Online

open access: yes, 2014
Information privacy is a cornerstone of library ethics. So why would we compromise that on library computers? Yet without our intervention, library patrons can have their behavior tracked when they use the web on our computers, or join our wireless ...
Salo, Dorothea
core  

Kirjaston kannalta hankalat aiheet ja sisällöt [PDF]

open access: yes, 2012
Tässä opinnäytetyössä pyrittiin selvittämään, mitkä ovat kirjastojen kannalta hankalia aiheita ja sisältöjä. Kirjastojen arvojen ja asenteiden lisäksi selvitettiin, miten ulkopuoliset tahot suhtautuvat hankaliin aiheisiin ja sisältöihin ja millaisia ...
Korkala, Antti
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Library ethics : a qualitative study of the ethical thoughts and experiences of a number of public libraries

open access: yes, 1997
The theme of this thesis is the professional ethics of public librarians. Qualitative interviews have been conducted with fourteen public librarians, with the aim to investigate their thoughts·and opinions concerning professional ethics and their ...
Larsson, Jeanin, Byström, Karin
core  

In Vivo Microplastic Detection With Photoacoustic Imaging

open access: yesAdvanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear   +9 more
wiley   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Conflict Situations in Work With Readers at Public Libraries

open access: yes, 2008
Bakalaura darbā „Konfliktsituācijas darbā ar lasītājiem publiskajās bibliotēkās” analizēti konflikti un to risināšanas īpatnības publisko bibliotēku darbā, īpaši akcentējot iespējamo konfliktu profilaksi un to profesionālu regulēšanu.
Mauriņa, Maija
core  

Ética e identidad en los servicios bibliotecológicos de la actual universidad cubana

open access: yes, 2020
The library context of the current university libraries in Cuba is subject to the influence of information and communication technologies, which is why constant adjustments are required to meet the most contemporary demands.
MarquesPolanco, Yennis   +2 more
core  

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

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