Results 41 to 50 of about 313,475 (267)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Jozef Oleszkiewicz as a Participant of an Academic Exhibition in 1814
Славянский мир в третьем тысячелетии, 2023 Jozef Oleszkiewicz, a native of the Polish-Lithuanian lands, was a talented portrait painter who settled on the banks of the Neva at the beginning of the 19th century and was elected academician of the Imperial Academy of Arts.
Kseniia Egorova
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Bibliothecae.it, 2023 This essay traces back the genesis, the bibliographic stratification and the history of the Library of Liceo Classico and Musicale «F. Petrarca», in Arezzo, starting from the constitution of its original core, attributable to the Library of the Jesuit ...
Maria Chiara Milighetti
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
BMGN: Low Countries Historical ReviewHigh medieval booklists are routinely interpreted as administrative sources that existed to inventory book collections, somewhat similar to present-day library catalogues. Historians, however, have found them curiously unreliable and impractical. A case
Tjamke Snijders
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Ever-evolving: introducing the Medical Heritage Library, Inc.
Journal of the Medical Library Association, 2019 The Medical Heritage Library, Inc. (MHL), is a collaborative digitization and discovery organization committed to providing open access to history of medicine and health resources.
Emily R. Novak Gustainis
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Bibliothek, 2022 Bibliotheken können in vielen Bereichen künstliche Intelligenz einsetzen. Machine Learning bietet vielversprechende Einsatzmöglichkeiten, unter anderem in der Erschließung von digitalisierten historischen Buchbeständen.
Krickl Martin +2 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source