Results 51 to 60 of about 2,433,933 (306)

York Digital Library : an ecological view of interactions and systems [PDF]

open access: yes, 2009
This case study of York Digital Library examines the development of a digital library of images at the University of York. In particular, it examines the project phase of the Fedora-based digital library and its provision of service to the History of Art
Allinson, J., Robertson, R.J.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Procedencias de los impresos de la biblioteca del Castillo Monasterio de Escornalbou : las marcas de propiedad de la colección de Eduard Toda

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2021
Objectives: this study analyses the provenance of the collection acquired by Eduard Toda in England which was then housed in his residence in the Escornalbou Castle-Monastery.
Pedro José Rueda Ramírez   +1 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Digitalisierung am Deutschen Museum – alles andere als retro

open access: yesLibrary Ideas, 2021
Die Digitalisierung und Onlinepräsentation von Buchbeständen ist in der Welt der Bibliotheken schon lange kein Novum mehr. Der Artikel beschreibt am Beispiel der Projekte der Bibliothek des Deutschen Museums die verschiedenen Formen von ...
Christian Winkler
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Ever-evolving: introducing the Medical Heritage Library, Inc.

open access: yesJournal of the Medical Library Association, 2019
The Medical Heritage Library, Inc. (MHL), is a collaborative digitization and discovery organization committed to providing open access to history of medicine and health resources.
Emily R. Novak Gustainis
doaj   +1 more source

HELIN Consortium LORI Grant United States Online History_Digital Repository Sites [PDF]

open access: yes, 2014
Description of state online history,digital repository sites, repared by: Emily Cuellar and Thomas Evans, Rhode Island State Library, July ...

core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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