Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang+11 more
wiley +1 more source
Flexibility-tuning of dual-display DNA-encoded chemical libraries facilitates cyclic peptide ligand discovery. [PDF]
Petrov D+10 more
europepmc +1 more source
Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng+5 more
wiley +1 more source
Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery. [PDF]
Nathan Kochen N+7 more
europepmc +1 more source
Assessing the Readiness for Implementing Linked Open Government Data: A Study on Indonesian Government Agencies' Library [PDF]
Irhamni Irhamni
openalex +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Genetic structuring and estimation of reproductive adults in Onchocerca volvulus: A genome-wide analysis across hosts and regions. [PDF]
Kumar P+12 more
europepmc +1 more source
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra+7 more
wiley +1 more source
Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art. [PDF]
Chaushevska M+6 more
europepmc +1 more source