Results 41 to 50 of about 3,639,878 (311)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Linguistics and LIS: A Research Agenda [PDF]

open access: yes, 2017
Linguistics and Library and Information Science (LIS) are both interdisciplinary fields that draws from areas such as languages, psychology, sociology, cognitive science, computer science, anthropology, education, and management. The theories and methods
Bolin, Mary K
core   +2 more sources

Answering the Calls of "What's Next" and "Library Workers Cannot Live by Love Alone" through Certification and Salary Research [PDF]

open access: yes, 2009
Members and staff of the American Library Association (ALA) worked diligently over more than a decade to develop a certification program for public library managers.
Grady, Jenifer
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Science and the Library

open access: yesCollege & Research Libraries, 1949
Made available in DSpace on 2013-01-29T15:41:33Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) crl_10_02_151_opt.pdf: 1078601 bytes, checksum: 0d5b899229b71fe6b805494841d7c8ad (MD5) Previous issue date: 1949-04 ; published or submitted for ...
openaire   +2 more sources

Managing complexity in a distributed digital library [PDF]

open access: yes, 1999
As the capabilities of distributed digital libraries increase, managing organizational and software complexity becomes a key issue. How can collections and indexes be updated without impacting queries currently in progress?
Apperley, Mark   +5 more
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

E-science and biomedical libraries

open access: yesJournal of the Medical Library Association : JMLA, 2009
For a few years now, segments of the research library community have been carefully tracking the emergence of e-science and exploring its implications for the future of research libraries. During 2007–2008, I had the opportunity to work with the Association of Research Libraries (ARL) and a task force looking at issues in e-science and library support ...
openaire   +2 more sources

"A Brilliant Mind": Margaret Egan and Social Epistemology [PDF]

open access: yes, 2004
Margaret Egan (1905???59) taught at the Graduate Library School of the University of Chicago (1946???55) and at the School of Library Science at Western Reserve University in Cleveland, Ohio (1955???59).
Furner, Jonathan
core  

Techtrends

open access: yes, 2000
Michio Kaku, author of Vis ions: How Science will Revolutionize the 21 \u27 Century, spoke at the most recent Texas Library Association conference in Dallas, Texas.
Matthews, Joe
core   +2 more sources

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