Results 31 to 40 of about 547,373 (313)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Priming for Advocacy: Revitalizing A 35-Year-Old Lecture Series

open access: yesMarketing Libraries Journal, 2020
Academic libraries face unique challenges by being a part of their larger institutions, such as a lack of visibility across campus. One solution to these challenges is advocacy, with one tool being an annual lecture series.
Broeder, Kathleen, Lanners, Emma
doaj  

Words matter: interpretations and implications of “para” in paraprofessional

open access: yesJournal of the Medical Library Association, 2021
Objective: While studies from the early 1990s show that library staff in nonlibrarian roles interpret the term “paraprofessional” as being demeaning to their roles, no recent research has been conducted on this topic.
Hannah Schilperoort   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Digital notetaking in lectures: how students adapt to a multi-faceted university learning environment

open access: yesCogent Education
University students are increasingly taking a digital approach to notetaking in lectures, influenced by technological developments, environmental sustainability, and the Covid-19 pandemic.
Beckie Arden   +3 more
doaj   +1 more source

It's All Improv to Me

open access: yesJournal of Play in Adulthood, 2022
Inspired by a workshop on incorporating improvisational techniques into classroom pedagogy, the in-class game Research Roulette was conceived as a way to incorporate improv and physical movement, with the specific goal of bringing a playful element into ...
Gina Levitan, Sarah Brooks Cohn
doaj   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

PUG-View: programmatic access to chemical annotations integrated in PubChem

open access: yesJournal of Cheminformatics, 2019
PubChem is a chemical data repository that provides comprehensive information on various chemical entities. It contains a wealth of chemical information from hundreds of data sources.
Sunghwan Kim   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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