Results 31 to 40 of about 215,799 (266)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Priming for Advocacy: Revitalizing A 35-Year-Old Lecture Series

Marketing Libraries Journal, 2020
Academic libraries face unique challenges by being a part of their larger institutions, such as a lack of visibility across campus. One solution to these challenges is advocacy, with one tool being an annual lecture series.
Broeder, Kathleen, Lanners, Emma
doaj  

Words matter: interpretations and implications of “para” in paraprofessional

Journal of the Medical Library Association, 2021
Objective: While studies from the early 1990s show that library staff in nonlibrarian roles interpret the term “paraprofessional” as being demeaning to their roles, no recent research has been conducted on this topic.
Hannah Schilperoort, Alvaro Quezada, Frances Lezcano   +2 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Digital notetaking in lectures: how students adapt to a multi-faceted university learning environment

Cogent Education
University students are increasingly taking a digital approach to notetaking in lectures, influenced by technological developments, environmental sustainability, and the Covid-19 pandemic.
Beckie Arden, Jennifer Norris, Steve Cole, Simon C. Gamble   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

It's All Improv to Me

Journal of Play in Adulthood, 2022
Inspired by a workshop on incorporating improvisational techniques into classroom pedagogy, the in-class game Research Roulette was conceived as a way to incorporate improv and physical movement, with the specific goal of bringing a playful element into ...
Gina Levitan, Sarah Brooks Cohn
doaj   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Directrius per a la preparació d'una bibliografia

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2002
Traducció al català de les Guidelines for the preparation of a bibliography de la RUSA’s Standards and Guidelines Committee. Aquestes directrius reflecteixen els desenvolupaments tecnològics des de l’àmplia difusió de les bibliografies a internet i fan ...
American Library Association. Reference and User Services Association
doaj  

Integrating Artificial Intelligence Tools for Research and Scholarly Communication in Academic Libraries: A Systematic Review

Open Information Science
The rapid advancement of artificial intelligence (AI) is reshaping research practices and scholarly communication within higher education institutions and academic libraries.
Simango Josina, Vilakazi Xolile, Ramabina Maropene Thomas   +2 more
doaj   +1 more source