Results 51 to 60 of about 4,573,689 (264)
Diversity, origin, and evolution of the ESCRT systems
Endosomal sorting complexes required for transport (ESCRT) play key roles in protein sorting between membrane-bounded compartments of eukaryotic cells.
Kira S. Makarova +8 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
YouTube Itak: a description of Ainu-related videos
The Ainu are an Indigenous group currently living primarily in Japan. Following the cultural revitalisation of laws and social movements and the appropriation of new technologies, Ainu communities are increasingly using social media to disseminate their ...
Xanat Vargas Meza +5 more
doaj +1 more source
York Digital Library : an ecological view of interactions and systems [PDF]
This case study of York Digital Library examines the development of a digital library of images at the University of York. In particular, it examines the project phase of the Fedora-based digital library and its provision of service to the History of Art
Allinson, J., Robertson, R.J.
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Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Background: The development of information technology has encouraged libraries to adopt innovations in their services, one of which is through a book proposal web service. Objective: This study aims to analyze the effectiveness of the utilization of the
Aura Aulia, Nadia Roosmalita Sari
doaj +1 more source
Using cost effectiveness analysis; a beginners guide [PDF]
Objective ‐ This report seeks to describe the key elements of cost effectiveness analysis (CEA) and to demonstrate how such analysis may be used in the library environment. Methods ‐ The paper uses a step‐by‐step approach to walk the non‐economist
Hulme, C.
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
What's New at the University of Alaska Southeast William A. Egan Library [PDF]
New Pacific Northwest Coast Art Brochures; New Wall Mounted Big Screen HDTVs; Sound Dampening added to 5 Study Rooms; Egan Library Open House; Changes to Departmental Copy Cards; 6 New Student Computer Workstations; Scan Directly to Email in the Library;
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