Results 41 to 50 of about 25,444,937 (291)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The University Library - an Intercultural and Multicultural Space

Revista Română de Biblioteconomie și Știința Informării, 2018
The 21st-century university library is a space hosting a multicultural education process, whether by design, with a clear strategy, or in an unstructured, yet natural manner. For that reason, my aim is to identify aspects of multiculturalism in the Eugen
Manuela Zănescu
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Few Words About Akribie

Information for Social Change, 1996
Akribie (which in German means the quality of exactness or accuracy), the Working Group of Critical Librarians, has been meeting since 1988. We work in libraries in West Germany, in all areas of specialisation.
Maria Kuhn-Ludewig
doaj   +1 more source

Use of EZProxy to access international journals among students of Library and Information Science, University of Indonesia

Record and Library Journal, 2016
Student’s magister is one of user library university of Indonesia those who need information regarding duty as carried out college.  With different backgrounds students as, made they need facilities sources of information easy and efficient.
Rusdiyah Ciptaning Dwi Kusuma
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Digital libraries: What do users want? [PDF]

, 2006
This is the post-print version of the Article of the Article. The official published version can be accessed from the link below - Copyright @ 2006 EmeraldPurpose – The purpose of this study is to determine user suggestions for digital libraries ...
Kani-Zabihi, E, Ghinea, G, Ghinea, Gheorghita, Chen, SY, Chen, Sherry Y., Kani-Zabihi, Elahe   +5 more
core   +1 more source

From a satisfied to the successful library user: conceptual and methodological elements of users research

Knjižnica, 2004
This paper deals with a specific segment of libraries’ activities which has been much exposed recently – the user. For the library of today, opinions of its users are no longer a curiosity; they are an important aspect of its research activities and also
Andrej Pinter
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source