Results 81 to 90 of about 25,444,937 (291)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Mobile web vs apps: what's right for your user? [PDF]
, 2011 With the advent of ever more sophisticated mobile devices, an increasing number of library users are ‘going mobile’, accessing the web and apps (AKA ‘downloadable applications’) whilst on the move.
Fletcher, J
core
Users’ expectations of public library services
Knjižnica, 2006 Public libraries are used by a wide range of users. Therefore they should offer as many different services as possible. The proper introduction of library services to the users can be monitored by measuring their expectations.
Tanja Borko +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Digital library for patents [PDF]
, 2002 The present paper discusses the concept of digital library and it’s significance, various motivating factors for digital library application are also highlighted briefly.
Chandra, Harish
core +1 more source
Educational Needs of Public Library Users
Knjižnica, 2014 Purpose: The article explains the role of user education in public libraries based on the assessment of users’ educational needs in a selected public library.
Simona Šinko
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Pattern of card catalogue consultation in a special library [PDF]
, 1986 A three day sample observation of card catalogue consultation by users at ISRO Satellite Centre (ISAC) Library has been made and results recorded. Users have been subsequently questioned about the purposes for which catalogue was consulted.
Sridhar, M. S.
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source