Results 91 to 100 of about 25,444,937 (291)

A Study on the Analysis of Public User Expectations for the Metaverse Library Services

Libri
This study examined the possibility of applying the Metaverse concept to the library, and to this end, we investigated representative Metaverse implementation cases and library implementation cases, analyzed them comprehensively, and discussed the ...
Noh Younghee
doaj   +1 more source

How to Explore Trends and Challenges for Building Future Libraries

Revista Română de Biblioteconomie și Știința Informării, 2019
Libraries need to use several different methods when determining the needs and wishes of students and academic patrons for future academic libraries and documentation centers.
Ane Landoy, Angela Repanovici
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

User preferences and library space at Whitworth University Library

Journal of Librarianship and Information Science, 2015
The design of library space is undergoing significant changes in layout and focus. Knowing that understanding a specific library’s user needs is essential to effective planning, many academic institutions have undertaken user studies to establish user needs prior to embarking on redesign, or update of library physical space.
Ojennus, Paul, Watts, Kathy A.
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Artificial Intelligence in Higher Education Institutions Libraries: Analyzing User Perceptions and Expectations

Open Information Science
This study investigates student perceptions of artificial intelligence (AI) adoption in university libraries, focusing on their understanding of AI’s benefits and ethical considerations essential for broader institutional implementation.
Kumar Rajender
doaj   +1 more source

Service Personalization in Digital Libraries: a Systematic Review of Research Trends, Techniques, and Future Directions [PDF]

Iranian Journal of Information Processing & Management
Delivering services in digital libraries must align with users’ preferences, needs, and feedback. In this context, service personalization plays a pivotal role in enhancing user satisfaction and maximizing the utilization of digital library capacities ...
Hossein Adabi Firozjah, Mitra Pashotanizade, Mehrdad Cheshmehsohrabi, Mehdi Alipourhafezi   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source