Results 111 to 120 of about 1,205,678 (309)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
MOBILE APPS OF LIBRARIES: BOON FOR LIBRARY USERS
Abstract The research paper attempts to describe the importance and adoption of introduction of mobile apps in the context of the library resources and services. As it is evident from the studies that, customized developed mobile apps will play a pivotal role in reaching out to library users in more effective way.
openaire +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Integrating Circulated Technology into the Library Collection Development Plan [PDF]
Academic libraries are increasingly focused on the acquisition and expansion of circulating technology collections. These collections are often governed by auxiliary library services such as Access Services or IT departments and not considered as part of
Ordinario, Neil
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
This study investigates student perceptions of artificial intelligence (AI) adoption in university libraries, focusing on their understanding of AI’s benefits and ethical considerations essential for broader institutional implementation.
Kumar Rajender
doaj +1 more source
IFLA statement on privacy in the library environment [PDF]
Introduction The rapid advancement of technology has resulted in increasing privacy implications for library and information services, their users, and society.
International Federation of Library Associations and Institutions
core
CLP LYNCS: Bringing a Library to the Pittsburgh Public Market [PDF]
Libraries are evolving and always thinking of new and creative ways to reach customers. The Carnegie Library of Pittsburgh devised a new initiative called the Library in Your Neighborhood, Community and School (LYNCS), and its first product was a new ...
Branning, Megan +2 more
core +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source

