Results 101 to 110 of about 2,625,846 (313)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Руды и металлыThe article presents results of the work for diamonds, base and precious metals, fulfilled in the Russian Federation under the "declaration principle" licenses since the mechanism came into effect.
Alekseev Ya. V. +2 more
doaj +1 more source
The European UTMS/IMT2000 license auctions
, 2001 We survey the recent European UMTS license auctions and compare their outcomes with the predictions of a simple model that emphasizes future market structure as a main determinant of valuations for licenses.
Jehiel, P., Moldovanu, B.
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Abiquiu, New Mexico, license to Antonio Leroux to trade only with the Comanches, no spirits, powder, lead or munitions, from James S. Calhoun. Copy. Transcript written by the author; annexed to James S. Calhoun, Superintendent of Indian Affairs.
core
, 1958 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a license substation opening up in Fort Worth for people to get their 1958 license ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Administrative means for legal protection of beaches - Study in Algerian legislation-Local Public Service Delegation as an effective local financing mechanism under Presidential Decree 15-247. [PDF]
مجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019 Algeria is a natural and human power. It has been blessed by a long coastline of 1644 km. It is of strategic importance in various economic fields: tourist and industrial, natural and human resources where the majority of the population is gathered, and ...
Tekarri Haifa Rachida
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source