Results 91 to 100 of about 2,625,846 (313)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PERJANJIAN LISENSI SEBAGAI BENTUK PERLINDUNGAN MEREK

open access: yesSASI, 2015
One branch of the study of the philosophy of science is the study of value axiology usefulness of science. Studies are generally intended to enhance human dignity.
Sarah Selfina Kuahaty
doaj  

Ten no-license years; a jubilee volume.

open access: yes, 1898
Title on spine: No license in Cambridge.Mode of access ...
Citizens' No-License Committee (Cambridge, Mass.)
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Licensing by modification Licensing by modification

open access: yesIlha do Desterro, 2008
Abstract: This paper looks at the phenomena of licensing by modification, whereby an unacceptable noun phrase is redeemed by the presence of a modifier or an unavailable reading for a noun phrase is made available with the addition of a modifier. It argues that an optimal account of such phenomena should derive these effects from the interaction ...
openaire   +1 more source

Sequential License Buyback Auctions: An Experimental Analysis

open access: yes
Fisheries managers use licenses as a method of capping the size of a fishing industry, but as management goals change and the size of fishery stocks fluctuate, managers may be faced with the decision to buy back licenses.
Freeman, Matthew A.   +1 more
core  

The European UMTS/IMT-2000 License Auctions [PDF]

open access: yes
We survey the recent European UMTS license auctions and compare their outcomes with the predictions of a simple model that emphasizes future market structure as a main determinant of valuations for licenses.
Moldovanu, Benny, Jehiel, Phillipe
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

License issued to Frank Riggs for Gambling

open access: yes
License issued February 4, 1863 from Brigadier General Joseph Rodman West, Headquarters, District of Arizona, Mesilla, Arizona, to Frank Riggs to keep, operate a gambling table, game, in Mesilla for fifteen days.

core  

Embedding a commitment to equitable global access into basic and early-phase translational research

open access: yesJournal of Clinical and Translational Science
The COVID-19 pandemic laid bare the inequities in U.S. healthcare in ways that captured public attention and reinforced the need to view all of healthcare through an equity lens. It also exposed global inequities in access to healthcare technologies.
Barry S. Coller
doaj   +1 more source

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