Results 71 to 80 of about 2,625,846 (313)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Competitive Analysis of Hardcore Restrictions in Technology Licensing Contracts [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī, 2013
Technology Licensing contract are agreements which pave the way for transferring and diffusing of technology. These agreements usually contain restrictive clauses which pose competitive concerns.
Mirghasem Jafarzadeh, Ebrahim Rahbari
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Myth of Political Liberty in Arthur Miller’s The crucible

open access: yesTraduction et Langues, 2017
This paper brings attention to the affinities between liberty and license in Arthur Miller’s the Crucible (1956). The play is an allegory for the ideology of McCarthyism which is based on questioning citizens for their Marxist orientations and accusing ...
Gandouz Ayeb Olfa
doaj  

Questions of improvement of financing of activity of businessmen and enterprise structures

open access: yesПутеводитель предпринимателя, 2020
In the article questions and problems of providing entrepreneurs and enterprise structures by available and acceptable financial (credit) means due to decrease in interest (credit) rates by banks are considered.
L. A. Akhmetov   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

ACCOUNTING FOR COMPUTER SOFTWARE COSTS [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Hundreds of thousands of companies all over the world use computers, with different software products and other useful applications. Nowadays, businesses need these modern tools.
TEIUŞAN SORIN-CIPRIAN
doaj  

Some questions of implementation of the national project on small and average business

open access: yesПутеводитель предпринимателя, 2020
In article problems and questions on implementation of the National project «Small and Average Business and Support ofan Individual Enterprise Initiative», financial aspects of implementation of the project till 2024 due to providing the provided ...
L. A. Akhmetov, D. A. Zuravlev
doaj  

Performance Evaluations of Technology Transfer Offices of Major US Research Universities in 2012/2013

open access: yesJournal of Technology Management & Innovation, 2014
By analyzing the highlights of the major activities reported by the technology transfer offices (TTOs) of twenty US major universities, the performances of TTO activities are quantitatively assessed and the associated scores are compared with each other.
Ampere A. Tseng, Miroslav Raudensky
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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