Results 51 to 60 of about 492,315 (257)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Legal Protection in The Use of Authentic Deeds in The Patent License Agreements

Alauddin Law Development Journal
This research examines the urgency of incorporating authentic deeds in patent licensing agreements and formulating such documents to establish legal safeguards that enhance the effectiveness of patent licensing ventures.
Silvia Sofiatunnisa Mulyana, Ranti Fauza Mayana, Elisatris Gultom   +2 more
doaj   +1 more source

Features in agreement and licensing

, 2022
AbstractChapter 5 brings the analyses in the previous chapters together, showing relations between parameter settings. The chapter first discusses ϕ features on heads in the clause, showing an implicational relation Appl > v > T, but ϕ on C is independent. This can be captured in a parameter hierarchy motivated by general learning biases.
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Trusted digital rights management protocol supporting for time and space constraint

Tongxin xuebao, 2008
A new content protection secure digital right management protocol was proposed,in which content object（CO） and rights object（RO） were separated respectively,and the CO was encrypted by content encryption key（CEK）,while RO was encapsulated by end user’s ...
MA Zhao-feng1, FAN Ke-feng2, CHEN Ming1, YANG Yi-xian1, NIU Xin-xin1   +4 more
doaj   +2 more sources

Contract regulation of commercial concession (franchising): problems of civil law development

Russian Journal of Economics and Law, 2014
Objective: to define the systems of legal regulation of commercial congcession (franchising) in the world practice. To reveal the features of commercial concession regulation in Russia.
N. A. Yushchenko, E. F. Gumerova
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Tailoring of K_0.8Al_0.7Fe_0.15Si_2.25O₆ Leucite Based Dental Ceramic Material

Croatica Chemica Acta, 2016
Potassium based ceramic materials composed from leucite in which 5 % of Al is exchanged with Fe and 4 % of hematite was synthesized by mechanochemical homogenization and annealing of K2O-SiO2-Al2O3-Fe2O3 mixtures.
Aleksandar Kremenović, Martin Fabián, Predrag Vulić, Čedomir Jovalekić, Jaroslav Briančin   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Umowy przenoszące autorskie prawa majątkowe na czas określony

Acta Iuris Stetinensis, 2015
The Act on copyright and related rights lists two types of agreements relating author’s economic rights: the copyright transfer agreement and the license agreement.
Joanna Szyjewska-Bagińska
doaj