Results 61 to 70 of about 492,315 (257)

Spectrophotometric Determination of Malondialdehyde in Urine Suitable for Epidemiological Studies

open access: yesCroatica Chemica Acta, 2016
A reliable method for spectrophotometric determination of urinary malondialdehyde (MDA), according to the thiobarbituric acid (TBA) assay, is described. To account for matrix interference and differences in individual urine composition, standard addition
Tin Weitner   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ISSUES OF CIVIL-LEGAL REGULATION AND CIVIL CIRCULATION OF INFORMATION

open access: yesRussian Journal of Economics and Law, 2008
The article views the issues of civil-legal regulation of information and the connected with it issue of ensuring of the civil circulation of information, as well as the means of regulation of those issues.
A. Ismanzhanov
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

MONOPOLI PADA LISENSI MEREK TERKENAL DAN KAITANNYA DENGAN PERSAINGAN USAHA

open access: yesMasalah-Masalah Hukum, 2013
This research conducted to ask two problems, can license wellknown trademark  support the competetion? and the dispute problems between licensor and licensee.
Agung Sujatmiko Bambang Sugeng
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Distinguishing between the notions of “commercial concession” and “franchising”

open access: yesRussian Journal of Economics and Law, 2014
RetractionDate: 02.05.2022Reason: Partial or full duplication of articles in the Actual Problems of Economics and Law Journal with previously published texts was detected.
N. A. Yushchenko
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Leveraging Elsevier’s Creative Commons License Requirement to Undermine Embargo

open access: yesJournal of Copyright in Education and Librarianship, 2018
In the last round of author-sharing policy revisions, Elsevier created a labyrinthine title-by-title embargo structure requiring embargoes from 12 to 48 months for authors sharing via institutional repository (IR), while permitting immediate sharing via ...
Josh Bolick
doaj   +1 more source

Home - About - Disclaimer - Privacy