Results 21 to 30 of about 318,687 (321)

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells

open access: yesFrontiers in Pharmacology, 2022
DNA replication initiation requires the loading of MCM2-7 complexes at the origins of replication during G1. Replication licensing renders chromatin competent for DNA replication and its tight regulation is essential to prevent aberrant DNA replication ...
Nikolaos Karantzelis   +10 more
doaj   +1 more source

How to protect the patent right in a standardization context—property rule or liability rule?

open access: yesMarket and Competition Law Review, 2023
High transaction costs are involved in the SEPs licensing process, and the FRAND policy essentially represents a collaborative effort by SSO members to reduce such costs.
Tyanyi Ren
doaj   +1 more source

Construct Validity of the Korean Dental Licensing Examination using Confirmatory Factor Analysis [PDF]

open access: yesJournal of Educational Evaluation for Health Professions, 2005
Confirmatory factor analysis based on a measurement model of a structural equation model was used to test the construct validity of 13 subjects in the Korean Dental Licensing Examination (KDLE).
Mi Kyoung Yim, Yoon Hee Kim
doaj   +1 more source

PENDAMPINGAN PRODUKSI SKALA KECIL, SOSIALISASI PEMASARAN DAN PERIZINAN TEH HERBAL ANTIOKSIDAN RAMBUT JAGUNG DESA SRAGI BLITAR [PDF]

open access: yes, 2021
The government launched the "One Village, One Product" program to encourage each village to have regional products. The products of the area can be packaged into creative economy efforts by prioritizing ideas and knowledge from human resources as the
Manshur, Hanif Alamudin   +2 more
core  

Enhancing Mesenchymal Stromal Cell Potency: Inflammatory Licensing via Mechanotransduction

open access: yesFrontiers in Immunology, 2022
Mesenchymal stromal cells (MSC) undergo functional maturation upon their migration from bone marrow and introduction to a site of injury. This inflammatory licensing leads to heightened immune regulation via cell-to-cell interaction and the secretion of ...
Max A. Skibber   +4 more
doaj   +1 more source

Replication Factors License Exonuclease I in Mismatch Repair [PDF]

open access: yesMolecular Cell, 2004
A key question in the eukaryotic mismatch repair field is how strand excision is coordinated with mismatch recognition. In a recent issue of Molecular Cell, Dzantiev et al. present evidence that the replication factors PCNA and RFC modulate the directionality of EXOI-mediated excision.
Surtees, Jennifer A, Alani, Eric
openaire   +2 more sources

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function

open access: yesBlood Advances, 2017
: Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. Here, we describe a time-dependent licensing process driven by GM-CSF in murine Ly6Chigh and human CD14+ monocytes that ...
Eliana Ribechini   +20 more
doaj   +1 more source

Deficiency in origin licensing proteins impairs cilia formation: implications for the aetiology of Meier-Gorlin syndrome.

open access: yesPLoS Genetics, 2013
Mutations in ORC1, ORC4, ORC6, CDT1, and CDC6, which encode proteins required for DNA replication origin licensing, cause Meier-Gorlin syndrome (MGS), a disorder conferring microcephaly, primordial dwarfism, underdeveloped ears, and skeletal ...
Tom Stiff   +7 more
doaj   +1 more source

Feasibility Testing of a Household Industry Food Production Certificate Using an Expert System with Forward Chaining Method

open access: yesJOIN: Jurnal Online Informatika, 2020
Quality and safe food products are the basic right of every consumer, including food products produced by small and medium industries. Good food production is an important factor in meeting quality standards or food safety licensing requirements.
Irfan Ardiansah   +3 more
doaj   +1 more source

Neutrophils Induced Licensing of Natural Killer Cells

open access: yesMediators of Inflammation, 2015
Natural killer (NK) cells acquire effector function through a licensing process and exert anti-leukemia/tumor effect. However, there is no means to promote a licensing effect of allogeneic NK cells other than cytomegalovirus reactivation-induced ...
Keishiro Amano   +5 more
doaj   +1 more source

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