Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang +3 more
wiley +1 more source
Folliculitis Decalvans and Lichen Planopilaris Phenotypic Spectrum-A Series of Four Patients.
Shanmugakumar S, Rai R, Gurusamy UM.
europepmc +1 more source
Global consensus on the management of melanin hyperpigmentation disorders
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron +9 more
wiley +1 more source
Successful treatment of lichen spinulosis with topical roflumilast: A case report. [PDF]
He R, Xu Y, Naert K, Chia JC.
europepmc +1 more source
Dermatology 2.0: Precision medicine for inflammatory skin diseases
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio +4 more
wiley +1 more source
Trichoscopic Differentiation in Alopecia: Retrospective Case Series Comparing Lichen Planopilaris, Discoid Lupus Erythematosus, and Alopecia Areata. [PDF]
Kaya G.
europepmc +1 more source
Chemical diversity of three lichens of genus Graphis (Graphidaceae) of the tropical dry forest from the northern region of Colombia [PDF]
Pierine España-Puccini +5 more
openalex +1 more source
Nemolizumab in prurigo nodularis up to 100 weeks: OLYMPIA LTE interim analysis
In this interim analysis of the OLYMPIA long‐term extension trial, nemolizumab exhibited sustained efficacy and was well tolerated through 100 weeks, with most adverse events being mild/moderate. Patients showed clinically meaningful improvements in core signs and symptoms.
Franz J. Legat +22 more
wiley +1 more source
Male external genital skin disorders: a retrospective analysis from a tertiary hospital in China. [PDF]
Qian YT +5 more
europepmc +1 more source
ABSTRACT Objetive To evaluate the influence of titanium and gold‐shaded titanium as well as peri‐implant soft tissue thickness on the optical outcome of implant‐supported lithium disilicate single crowns. Methods Eighteen patients received an anterosuperior implant (Astra Tech Implant System EV). Two customized titanium abutments (gold and conventional)
Francisco Martínez‐Rus +4 more
wiley +1 more source

