Results 211 to 220 of about 84,226 (311)

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann   +7 more
wiley   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Lichenoid and Granulomatous Stomatitis: Three Additional Cases and Detailed Immunohistochemical Analysis

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Lichenoid and granulomatous stomatitis (LGS) is a rare condition, with clinicopathological features resembling lichenoid and granulomatous dermatitis. Despite increasing reports, its etiology remains unclear and detailed immunohistochemical (IHC) studies are lacking.
Mariana Paravani Palaçon   +12 more
wiley   +1 more source

Utility of IL‐18 Immunohistochemistry in Distinguishing Dermatomyositis and Lupus Erythematosus in Skin Biopsies

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinction of dermatomyositis (DM) and cutaneous lupus erythematosus (LE) in skin biopsies is often difficult due to significant histopathologic overlap. Prior transcriptional analysis has identified upregulation of IL‐18 in DM compared with LE.
Steven M. Hrycaj   +8 more
wiley   +1 more source

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