Development of a nalmefene formulation suitable for a community‐use auto‐injector
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Listening to Hong Kong children's perspectives through pretend play
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley +1 more source
AI voice journaling for future language teachers: A path to well‐being through reflective practices
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley +1 more source
Safety and effectiveness of Bian-stone and moxibustion in treatment of meibomian gland dysfunction. [PDF]
Hao R, Bai XM, Jing DL, Jiang XD, Li XM.
europepmc +1 more source
English teachers' journeys since the 2020 Iteration of Black Lives Matter
Abstract The 2020 resurgence of Black Lives Matter (BLM) mobilised students in England to demand greater representation of racially minoritised voices in English curriculums—a call highlighted by stark inequity: just 1.5% of GCSE texts studied are by racially minoritised authors, despite racially minoritised students comprising 38.0% of the student ...
Adrian Fernandes
wiley +1 more source
Comparison of Meibomian Gland Loss Between Pediatric Patients with Blepharo-Keratoconjunctivitis and Age-Matched Controls Using Non-Contact Meibography. [PDF]
Jeong J, Paik JS, Na KS, Cho K.
europepmc +1 more source
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley +1 more source
Self-Supervised OCT Representation Learning with Local Dimensionality Regularization for Automated Retinal Disease Diagnosis. [PDF]
Sun X, Lin W, Yuan C, Xu J, Luo Y.
europepmc +1 more source
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner +4 more
wiley +1 more source
Comparative efficacy of eyelid cleansing wipes, hypochlorous acid, and saline for blepharitis-associated ocular surface disease: a randomized trial. [PDF]
Shi R, Guo Y, Li A, Tian L, Jie Y.
europepmc +1 more source

