Eyelid and tear-film factors associated with contact lens discomfort symptom burden among wearers attending after-care in Kisumu County, Kenya: a clinic-based cross-sectional study. [PDF]
Muga S +3 more
europepmc +1 more source
Structure and Dynamics of Porin Loops in Asymmetric Outer Membranes of E. coli
What are loops of membrane proteins doing within the oligosaccharide coat of cells? This structurally unexplored space is studied by solid‐state NMR, with the outer membrane protein G (OmpG) embedded in asymmetric E. coli outer membrane (OM) vesicles as a paradigmatic example.
Morgane Adélaïde +13 more
wiley +1 more source
Live Respiratory Syncytial Virus Vaccine D46/cp/ΔM2-2 Is Overattenuated in RSV-Seronegative Children. [PDF]
Karron RA +7 more
europepmc +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Hierarchical geometric deep learning enables scalable analysis of molecular dynamics. [PDF]
Pengmei Z +3 more
europepmc +1 more source
Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham +3 more
wiley +1 more source
Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta-Analysis. [PDF]
Nóbrega-Sousa P +5 more
europepmc +1 more source
Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz +2 more
wiley +1 more source
A Narrative Inquiry of Meaning Making and Leader Identity Development among College Students. [PDF]
Sunderman HM +5 more
europepmc +1 more source
ABSTRACT In this paper we describe a technique to make a confined environment of variable stiffness that is suitable for high‐resolution live‐cell imaging. This versatile and adaptable technique enables cell confinement between soft elastic surfaces made from polyacrylamide gels.
Alexia Caillier, Patrick W. Oakes
wiley +1 more source

