Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham +3 more
wiley +1 more source
Self-Supervised OCT Representation Learning with Local Dimensionality Regularization for Automated Retinal Disease Diagnosis. [PDF]
Sun X, Lin W, Yuan C, Xu J, Luo Y.
europepmc +1 more source
Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz +2 more
wiley +1 more source
Safety and effectiveness of Bian-stone and moxibustion in treatment of meibomian gland dysfunction. [PDF]
Hao R, Bai XM, Jing DL, Jiang XD, Li XM.
europepmc +1 more source
ABSTRACT In this paper we describe a technique to make a confined environment of variable stiffness that is suitable for high‐resolution live‐cell imaging. This versatile and adaptable technique enables cell confinement between soft elastic surfaces made from polyacrylamide gels.
Alexia Caillier, Patrick W. Oakes
wiley +1 more source
Comparison of Meibomian Gland Loss Between Pediatric Patients with Blepharo-Keratoconjunctivitis and Age-Matched Controls Using Non-Contact Meibography. [PDF]
Jeong J, Paik JS, Na KS, Cho K.
europepmc +1 more source
Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed +5 more
wiley +1 more source
Clinical features, treatment outcomes, and risk factors for surgery in pediatric chalazion. [PDF]
Samant M +4 more
europepmc +1 more source
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang +6 more
wiley +1 more source
Comparative efficacy of eyelid cleansing wipes, hypochlorous acid, and saline for blepharitis-associated ocular surface disease: a randomized trial. [PDF]
Shi R, Guo Y, Li A, Tian L, Jie Y.
europepmc +1 more source

