Results 81 to 90 of about 770,641 (335)

Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. [PDF]

open access: yes, 2019
The 26S proteasome is essential for proteostasis and the regulation of vital processes through ATP-dependent degradation of ubiquitinated substrates. To accomplish the multi-step degradation process, the proteasomes regulatory particle, consisting of lid
Aufderheide   +42 more
core   +1 more source

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid   +6 more
wiley   +1 more source

Implementing universal design in a Norwegian context: Balancing core values and practical priorities

open access: yesDisability Studies Quarterly, 2016
How can urban planning processes include perspectives from people with disabilities? This paper discusses the implementation of universal design (UD) and accessibility in a local urban context.
Inger Marie Lid
doaj   +1 more source

Evaluating the Impact of Low Impact Development (LID) Practices on Water Quantity and Quality under Different Development Designs Using SWAT

open access: yes, 2017
The effects of Low Impact Development (LID) practices on urban runoff and pollutants have proven to be positive in many studies. However, the effectiveness of LID practices can vary depending on different urban patterns.
M. Seo   +3 more
semanticscholar   +1 more source

A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I

open access: yesJournal of Biological Chemistry, 2017
Lecithin:cholesterol acyltransferase (LCAT) plays a key role in reverse cholesterol transport by transferring an acyl group from phosphatidylcholine to cholesterol, promoting the maturation of high-density lipoproteins (HDL) from discoidal to spherical ...
K. Manthei   +10 more
semanticscholar   +1 more source

Multipurpose Transparent Nanocomposites for Gamma Spectroscopy, Pulse Shape Discrimination, Thermal Neutron Detection, Radiation Shielding, and High Refractive Index Applications

open access: yesAdvanced Functional Materials, EarlyView.
Materials exist that are useful for gamma scintillation, radiation shielding, neutron‐gamma pulse shape discrimination (PSD), thermal neutron detection, or high refractive index applications. While certain materials have exhibited optimal performance for each of these applications, none achieve multiple functions.
Isabelle Winardi   +13 more
wiley   +1 more source

Simulation of Low Impact Development (LID) Practices and Comparison with Conventional Drainage Solutions

open access: yesProceedings, 2018
The present work aims at quantifying the benefit of Low Impact Development (LID) practices in reducing peak runoff and runoff volume, and at comparing LID practices to conventional stormwater solutions.
I. Kourtis, V. Tsihrintzis, E. Baltas
semanticscholar   +1 more source

Sustainable Catalyst‐Free PLG Networks: Recyclability, Biodegradability, and Functional Performance

open access: yesAdvanced Functional Materials, EarlyView.
A catalyst‐additive free covalent adaptable network is developed from star‐shaped poly(lactide‐co‐glycolide) cross‐linked with pyromellitic dianhydride, enabling internal carboxylic acid‐driven transesterification. The resulting biodegradable network exhibits mechanical robustness (Young's modulus ≈1.6 GPa), complete recyclability, rapid biodegradation
Lars Schwarzer   +2 more
wiley   +1 more source

From Institutionalisation to Citizenship: Lessons Learned from Studying Diaconal Practice in a Norwegian Context

open access: yesDiaconia, 2019
This article is based upon a historical study of a Norwegian diaconal foundation working in the field of disability care and welfare services. The article discusses how the foundation understood their mission and responded to emerging ...
Inger Marie Lid
doaj   +1 more source

Choice of Location and the Roles of Foreign Subsidiaries: Evidence from UK Regions [PDF]

open access: yes
In this paper we investigate the location determinants of inward foreign direct investment (FDI) in the UK at a regional level. The paper focuses on a relatively under investigated field, that of the linkage between choice of regional location- within a ...
Constantina Kottaridi   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy