Results 1 to 10 of about 7,655 (129)

A Solute Gradient in the Tear Meniscus. II. Implications for Lid Margin Disease, including Meibomian Gland Dysfunction [PDF]

Ocular Surface, 2011
We have hypothesized previously that evaporation from the tears generates a solute gradient across the tear meniscus, which delivers hyperosmolar stress to the mucocutaneous junction (MCJ) of the lid margin. This is proposed as the basis for Marx's line, a line of staining with topically applied dyes that lies directly behind the MCJ.
Anthony J Bron, Norihiko Yokoi, Eamonn A Gaffney   +2 more
exaly   +4 more sources

Lid Margin Microbiome in Stevens-Johnson Syndrome Patients With Lid Margin Keratinization and Severe Dry Eye Disease

Investigative Ophthalmology & Visual Science
The current study evaluated the lid margin microbiome of keratinized lid margins of patients with chronic Stevens-Johnson syndrome (SJS) and compared it with healthy controls and historically reported lid margin microbiome of patients with meibomian gland dysfunction (MGD).Eyelid margin swabs of 20 asymptomatic adults (mean age = 29 ± 12 years) and 10 ...
Swati Singh, Kotakonda Arunasri, Sayan Basu   +2 more
exaly   +3 more sources

Characteristics of the meibomian gland in a population without dry eye symptoms [PDF]

Scientific Reports
This cross-sectional study examined morphological and functional changes of the meibomian glands in 60 volunteers without dry eye symptoms, stratified into age groups of 31–40, 41–50, and 51–60 years.
Sathiya Kengpunpanich, Pinnita Prabhasawat, Rawi Jongpipatchai, Chareenun Chirapapaisan, Panotsom Ngowyutagon, Wipawee Booranapong   +5 more
doaj   +2 more sources

Predictive performance of corneal and lid margin sensitivity for dry eye disease: An investigator-masked, prospective, prognostic accuracy study

Ocular Surface
To evaluate the prognostic ability of non-contact esthesiometry corneal and lid margin sensitivity measurements in detecting symptoms and signs of dry eye disease, as defined by the global consensus TFOS DEWS II criteria.A total of 87 community residents (58 females; mean ± SD age, 53 ± 16 years) were recruited in an investigator-masked, prospective ...
Michael T M Wang, Ally L Xue, Barry Power   +2 more
exaly   +4 more sources

Association between lid margin collarettes and dry eye disease severity in the Dry Eye Assessment and Management (DREAM) study. [PDF]

Eye (Lond)
Abstract Background/objectives Lid margin collarettes are a distinct clinical finding and their association with meibomian gland dysfunction (MGD) and dry eye symptoms and signs remains uncertain.
Azar AE, Haddad EN, Augello PA, Lin MC, Ying GS, Asbell PA, Sayegh RR, Dry Eye Assessment and Management (DREAM) Study Research Group.   +7 more
europepmc   +4 more sources

Therapeutic outcomes of oral cefcapene in meibomitis-related keratoconjunctivitis: A Propensity-matched cohort study [PDF]

Taiwan Journal of Ophthalmology
PURPOSE: The purpose of the study was to evaluate the clinical characteristics and therapeutic response in patients with meibomitis-related keratoconjunctivitis (MRKC) who were treated with oral cefcapene pivoxil hydrochloride hydrate, and to determine ...
Ella (Seo Yeon) Park, Hyunmin Ahn, Kyoung Yul Seo   +2 more
doaj   +2 more sources

Impacts of gender and age on meibomian gland in aged people using artificial intelligence

Frontiers in Cell and Developmental Biology, 2023
Purpose: To evaluate the effects of age and gender on meibomian gland (MG) parameters and the associations among MG parameters in aged people using a deep-learning based artificial intelligence (AI).Methods: A total of 119 subjects aged ≥60 were enrolled.
Binge Huang, Fangrong Fei, Han Wen, Ye Zhu, Zhenzhen Wang, Shuwen Zhang, Liang Hu, Wei Chen, Qinxiang Zheng   +8 more
doaj   +1 more source

A beginner's guide to mucous membrane grafting for lid margin keratinization: Review of indications, surgical technique and clinical outcomes

Indian Journal of Ophthalmology, 2021
The posterior lid margin, where the mucocutaneous junction (MCJ) between the eyelid skin and tarsal conjunctiva is located, plays a critical role in maintaining the homeostasis of the ocular surface.
Swapna S Shanbhag, Swati Singh, Puduchira George Koshy, Pragnya Rao Donthineni, Sayan Basu   +4 more
doaj   +1 more source

Correlative factors of ocular surface lesions after allogeneic hematopoietic stem cell transplantation: A retrospective study

Frontiers in Oncology, 2022
BackgroundOcular graft-versus-host disease (oGVHD) is one of the complications after allogeneic hematopoietic stem cell transplantation (HSCT), which impairs the quality of life and may indicate poor prognosis. In this retrospective study, the aim was to
Xin-Yu Zhuang, Zheng-Tai Sun, Yue Xu, Ya-Ru Ren, Ying-Jie Chen, Feng Chen, Feng Chen, Xiao Ma, Xiao Ma, Xiao-Wen Tang, Xiao-Wen Tang, Xiao-Feng Zhang, Xiao-Feng Zhang   +12 more
doaj   +1 more source

Bevacizumab Eye Drops Vs. Intra-meibomian Gland Injection of Bevacizumab for Meibomian Gland Dysfunction-Associated Posterior Blepharitis

Frontiers in Medicine, 2022
AimsThis study aimed to evaluate the efficacy and safety of bevacizumab eye drops compared with those of an intra-meibomian gland (MG) injection of bevacizumab when performed in conjunction with standard lid hygiene in patients with meibomian gland ...
Chitchanok Tantipat, Ngamjit Kasetsuwan, Ngamjit Kasetsuwan, Patraramon Chotikkakamthorn, Krit Pongpirul   +4 more
doaj   +1 more source