Results 111 to 120 of about 148,325 (342)

Effects of Buffering and Preparation Time of Topical Anesthetics on Pain of Injection into Oral Mucosa

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: Many dental patients are afraid of injections. There are different methods for reducing pain during topical anesthetic injections. Some studies have reported buffering lidocaine to reduce injection pain.
Nasser Kaviani   +3 more
doaj  

The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB Activation

open access: yesMediators of Inflammation, 2013
Lidocaine, a common local anesthetic drug, has anti-inflammatory effects. It has demonstrated a protective effect in mice from septic peritonitis. However, it is unknown whether lidocaine has effects on high mobility group box 1 (HMGB1), a key mediator ...
Huan-Liang Wang   +5 more
doaj   +1 more source

Strategy‐Level Prodrug Synthesis

open access: yesChemistry – A European Journal, EarlyView.
Prodrug approaches can be expanded by increasing options for controlling site‐selective functionalization, boosting the range of linking groups, and enhancing the chemoselectivity of reactive group incorporation. This Concept describes strategy‐level prodrug synthesis, whereby these issues are addressed at an early stage of a sequence.
Paul J. Geaneotes, Paul E. Floreancig
wiley   +1 more source

Lidocaine inhibits proliferation and metastasis of lung cancer cell via regulation of miR-539/EGFR axis

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Background Despite the medical uses of lidocaine has been well-characterized, the study of lidocaine’s pharmacological function other the anaesthetic effect was never stopped.
Hai Sun, Yan Sun
doaj   +1 more source

Anthraquinone Sulfonates as Water‐Soluble Photocatalysts: Synthetic Applications and Perspectives

open access: yesChemPhotoChem, EarlyView.
The development of photochemistry in water is rapidly advancing, and the demand for water‐soluble photocatalysts is increasing. Accordingly, anthraquinone sulfonates are interesting options for the activation of organic molecules through H‐atom transfer, proton‐coupled electron transfer, or the generation of reactive oxygen species.
Daniel Kolb   +2 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang   +6 more
wiley   +1 more source

Effect of meloxicam and lidocaine administered alone or in combination on indicators of pain and distress during and after knife castration in weaned beef calves.

open access: yesPLoS ONE, 2018
To assess the effect of meloxicam and lidocaine on indicators of pain associated with castration, forty-eight Angus crossbred beef calves (304 ± 40.5 kg of BW, 7-8 months of age) were used in a 28 day experiment.
Daniela M Meléndez   +8 more
doaj   +1 more source

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