Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer
Ovarian and breast cancer are prevalent female malignancies with increasing occurrence incidence and metastasis, significantly affecting the health and life quality of women globally.
Dan Sun, Ying-Chun Li, Xiao-Yu Zhang
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Drug distribution in dorsal root ganglion after peripheral application of Lidocaine patch [PDF]
This study investigated lidocaine distribution following patch application at peripheral position. The study included three parts. Animals in Part A (n = 12) were received 5% lidocaine patches on paravertebral (Group A1) or parasternal (Group A2) side ...
Geng Xu+5 more
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Background Despite the medical uses of lidocaine has been well-characterized, the study of lidocaine’s pharmacological function other the anaesthetic effect was never stopped.
Hai Sun, Yan Sun
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Neurotropin protects rotator cuff tendon cells from lidocaine-induced cell death [PDF]
Background Local anesthetics often are used in rotator cuff tears as therapeutic tools, although some cases have reported that they have detrimental effects. Neurotropin (NTP) is used widely in Japan as a treatment for various chronic pain conditions and
Ryunosuke Abe+8 more
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Magnesium Sulfate versus Tramadol as Adjuvants to Lidocaine in Intravenous Regional Anesthesia for Carpal Tunnel Release Surgery: A Randomized Clinical Study [PDF]
Background: Intravenous regional anesthesia [IVRA] is a simple and effective anesthetic method for providing regional anesthesia of the upper limbs during carpal tunnel release surgery [CTRS].
Khaled Elsheshtawy+2 more
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Simple Summary The local anesthetic lidocaine suppresses some cancer cell lines but the mechanism is unclear. Melastatin-like transient receptor potential 7 (TRPM7) ion channels play a role in cancer and may be a target for lidocaine.
Hengrui Liu, J. Dilger, Jun Lin
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The Effect of Different Local Anesthesia Methods on Pain Relief in Outpatient Endometrial Biopsy: Randomized Clinical Trial [PDF]
Introduction: Endometrial biopsy is necessary for diagnosing the reason of abnormal uterine bleeding in perimenopausal women. Currently outpatient endometrial biopsy is used for evaluation of abnormal uterine bleeding which is associated with moderate to
Elaheh Olad-Saheb-Madarek+3 more
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Evaluation of Lidocaine and Metabolite Pharmacokinetics in Hyaluronic Acid Injection
Lidocaine-incorporated hyaluronic acid injection (LHA) is considered a promising way to increase patient compliance. Various reviews and analyses have been conducted to verify that the addition of lidocaine had no effect on the product quality of ...
Ju Hee Kim+5 more
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Comparison of Lidocaine-Distilled Water and Lidocaine-Mgso4 Mixture in Epidural Anesthesia of Dog [PDF]
Objective- To compare the lidocaine-MgSO4 combination with lidocaine-Distilled water inthe epidural of indigenous awake dogs.Design- Prospective experimental study.Animals- Five young (12±2 months) female indigenous dogs weighting (10.74 ± 0.44 kg ...
Seifollah Dehghani, Amin Bigham Sadegh
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