Results 201 to 210 of about 79,534 (262)
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Therapeutic Drug Monitoring, 2000
Lidocaine has a concentration-dependent effect on seizures. At lower concentrations it has anticonvulsant properties, whereas concentrations above 15 microg/mL frequently result in seizures in laboratory animals and man. Seizures induced by lidocaine in experimental conditions invariably start in the amygdala.
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Lidocaine has a concentration-dependent effect on seizures. At lower concentrations it has anticonvulsant properties, whereas concentrations above 15 microg/mL frequently result in seizures in laboratory animals and man. Seizures induced by lidocaine in experimental conditions invariably start in the amygdala.
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Annals of Emergency Medicine, 1980
Lidocaine is recognized as a first line drug for ventricular arrhythmias and has recently been used in acute myocardial infarction as prophylaxis against ventricular fibrillation. A 68-year-old man was erroneously given 2 gm of lidocaine by intravenous push and sustained a cardiac arrest. He was treated supportively and had complete recovery.
D L, Brown, J J, Skiendzielewski
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Lidocaine is recognized as a first line drug for ventricular arrhythmias and has recently been used in acute myocardial infarction as prophylaxis against ventricular fibrillation. A 68-year-old man was erroneously given 2 gm of lidocaine by intravenous push and sustained a cardiac arrest. He was treated supportively and had complete recovery.
D L, Brown, J J, Skiendzielewski
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Acta Anaesthesiologica Scandinavica, 1981
In 32 patients undergoing spinal anaesthesia with lidocaine or lidocaine plus adrenaline, the concentration of lidocaine base was measured in repeated venous blood samples. Half of the patients were given 100 mg lidocaine alone and the other half 100 mg lidocaine with the addition of 0.2 mg adrenaline.
K. Axelsson, B. Widman
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In 32 patients undergoing spinal anaesthesia with lidocaine or lidocaine plus adrenaline, the concentration of lidocaine base was measured in repeated venous blood samples. Half of the patients were given 100 mg lidocaine alone and the other half 100 mg lidocaine with the addition of 0.2 mg adrenaline.
K. Axelsson, B. Widman
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Pain, 1992
Ten patients with organic nerve injury causing chronic neuropathic pain were tested for the effects of intravenous lidocaine versus saline upon psychophysical somatosensory variables. The variables assessed were the subjective magnitude of pain, area of mechanical hyperalgesia and presence and magnitude of thermal heat/cold hyperalgesia.
Claudio Marangoni +5 more
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Ten patients with organic nerve injury causing chronic neuropathic pain were tested for the effects of intravenous lidocaine versus saline upon psychophysical somatosensory variables. The variables assessed were the subjective magnitude of pain, area of mechanical hyperalgesia and presence and magnitude of thermal heat/cold hyperalgesia.
Claudio Marangoni +5 more
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Concentrations of Lidocaine and Monoethylglycylxylidide (MEGX) in Lidocaine Associated Deaths
Journal of Forensic Sciences, 1985Abstract Concentrations of lidocaine and MEGX were determined in a variety of tissues and other samples collected at autopsy. In 13 of the cases examined in which lidocaine was associated with death, tissue concentrations were greater than 15 mg/kg. Tissue concentrations in other patients treated with lidocaine were significantly lower.
Michael A. Peat +4 more
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Mechanism of Lidocaine Release From Carbomer–Lidocaine hydrogels
Journal of Pharmaceutical Sciences, 2002Rheology, acid-base behavior, and kinetics of lidocaine release of carbomer-lidocaine (C-L) hydrogels are reported. A series of (C-L)(x) (x = mol% of L = 25, 50, 75, 100) that covers a pH range between 5.33 and 7.96 was used. Concentrations of ion pair ([R-COO(-)LH(+)]) and free species (L) and (LH(+)) were determined by the selective extraction of (L)
Ruben H. Manzo +2 more
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JAMA: The Journal of the American Medical Association, 1977
To the Editor.— This letter refers to the article "Pharmacokinetic Approach to the Clinical Use of Lidocaine Intravenously" (236:273, 1976) by Greenblatt et al. I would like to call attention to a possible problem with the data on which they base their approach. Greenblatt and colleagues base their analysis on the data in an article by Rowland et al.
Lewis B. Sheiner +2 more
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To the Editor.— This letter refers to the article "Pharmacokinetic Approach to the Clinical Use of Lidocaine Intravenously" (236:273, 1976) by Greenblatt et al. I would like to call attention to a possible problem with the data on which they base their approach. Greenblatt and colleagues base their analysis on the data in an article by Rowland et al.
Lewis B. Sheiner +2 more
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Best Practice & Research Clinical Anaesthesiology, 2017
Lidocaine has analgesic effect and antihyperalgesic and anti-inflammatory properties, which enable its use as a general anesthetic adjuvant. Lidocaine can reduce nociception and/or cardiovascular responses to surgical stress, postoperative pain, and/or analgesic requirements. However, its mechanisms of action remain unclear, despite its different known
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Lidocaine has analgesic effect and antihyperalgesic and anti-inflammatory properties, which enable its use as a general anesthetic adjuvant. Lidocaine can reduce nociception and/or cardiovascular responses to surgical stress, postoperative pain, and/or analgesic requirements. However, its mechanisms of action remain unclear, despite its different known
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Fentanyl and lidocaine versus lidocaine for Bier block.
Regional anesthesia, 1992The present study was designed to assess the efficacy of fentanyl combined with dilute lidocaine solution for intravenous regional anesthesia of the arm.In ten volunteers, the nondominant arm was exposed to three treatments: 100 mg lidocaine, 42 ml; 100 mg lidocaine plus 100 micrograms fentanyl, 42 ml; and 100 micrograms fentanyl, 42 ml.
Jeff M. Arthur +3 more
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LIDOCAINE IN CARDIAC ARRHYTHMIAS
Survey of Anesthesiology, 1968Sixty unanesthetized patients with 74 cardiac arrhythmias received lidocaine intravenously in an average dose of 1.5 mg/kg in 30 seconds. Suppression or termination of ventricular arrhythmias occurred in more than 80% of the 33 patients whether they had an acute myocardial infarction, were receiving digitalis, or were not receiving digitalis or ...
Lawrence A. Lubow +3 more
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