Exploring the Effect of Botulinum Toxin A - Lidocaine on Experimental Abdominal Wall Defect Healing in Rats [PDF]
The aim of this study was to investigate the effects of Botulinum Toxin A (Botox) and lidocaine on the repair of abdominal muscle defects. This study was conducted on 40 rats in four groups.
Seyed Reza Hashemi+3 more
doaj +1 more source
New patents on topical anesthetics. [PDF]
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano+6 more
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Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A.+3 more
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Combination of pharmacotherapy and lidocaine analgesic block of the peripheral trigeminal branches for trigeminal neuralgia: a pilot study [PDF]
Classical trigeminal neuralgia (CTN) is treated predominantly by pharmacotherapy but side effects and unsuccessful occurs. The current study was carried out to evaluate the therapeutic effect of combination of pharmacotherapy and lidocaine block ...
Bruti, Gianluca+9 more
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Jeffrey Gudin,1,2 Lynn R Webster,3 Emileigh Greuber,4 Kip Vought,4 Kalpana Patel,4 Louis Kuritzky5 1Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ, USA; 2Department of Anesthesiology and Pain Management, Englewood Hospital ...
Gudin J+5 more
doaj
Development and Field Validation of Lidocaine-Loaded Castration Bands for Bovine Pain Mitigation
Castration is among the most common management procedures performed in the dairy and beef cattle industries and is mainly performed by surgery or elastic banding.
James W. Saville+11 more
doaj +1 more source
Capsazepine prolongation of the duration of lidocaine block of sensory transmission in mice may be mediated by modulation of HCN channel currents [PDF]
Background and objectives Hyperpolarization-activation cyclic nucleotide-gated (HCN) channels contribute to the effects of lidocaine. Capsazepine (CPZ), a competitive inhibitor of capsaicin of transient receptor potential vanilloid-1 channel, has also ...
Wenling Zhao+7 more
doaj +2 more sources
Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa+4 more
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Emerging pharmacotherapy of tinnitus [PDF]
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen+43 more
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Molecular mechanisms of lidocaine
Lidocaine is an amide-class local anesthetic used clinically to inhibit pain sensations. Systemic administration of lidocaine has antinociceptive, antiarrhythmic, anti-inflammatory, and antithrombotic effects. Lidocaine exerts these effects under both acute and chronic pain conditions and acute respiratory distress syndrome through mechanisms that can ...
Resiana Karnina+3 more
openaire +2 more sources