Results 41 to 50 of about 467,532 (268)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Jurisprudential analysis of the mafia game; Emphasizing the elements of lies, deception and the nature of play [PDF]

پژوهش‌های فقهی مسائل مستحدثه
Mafia game; Emerging and pervasive entertainment among Muslim youth. Since in this game, the approach of the mafia members is to lie and deceive the citizens of the game, the jurisprudential evidence of banning falsehood (lying as a joke) has attracted ...
mohamad hasanzadeh
doaj   +1 more source

P300 as a correlate of false beliefs and false statements

Brain and Behavior, 2023
Introduction This study investigates P300 as a component for false belief and false statement processing with and without a communicative context. The purpose is to understand why P300 has been shown to be commonly involved in false belief and lie ...
Yang Wang, Carrey Tik Sze Siu, Him Cheung   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Weak Lie symmetry and extended Lie algebra [PDF]

Journal of Mathematical Physics, 2013
The concept of weak Lie motion (weak Lie symmetry) is introduced. Applications given exhibit a reduction of the usual symmetry, e.g., in the case of the rotation group. In this context, a particular generalization of Lie algebras is found (“extended Lie algebras”) which turns out to be an involutive distribution or a simple example for a tangent Lie ...
openaire   +4 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Most Important Causes for Weakening the Extremist Narrators (Ghalis) [PDF]

تحقیقات علوم قرآن و حدیث, 2016
From the perspective of scholars of hadith, accepting and trusting the narratives of a narrator depends on a variety of factors, lack of each result in distrust.
Sayede Zeynab Toloue Hashemi, Seyed Kazem Tabatabaeipour, Mahdi Jalali, Seyed Mohammad Emamzadeh   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Who lies to protect another? Motivational, behavioral, and socio-cognitive predictors of children’s interventional deception

Psychology of Language and Communication
The objective of the current study was to examine how the expected rewards, theory of mind, and false praise-telling relate to interventional deception that prevents moral transgression.
Płotnikowska Joanna, Filip Anna
doaj   +1 more source

Historical Techniques of Lie Detection

Europe's Journal of Psychology, 2015
Since time immemorial, lying has been a part of everyday life. For this reason, it has become a subject of interest in several disciplines, including psychology.
Martina Vicianova
doaj   +1 more source