Results 61 to 70 of about 467,532 (268)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Integrity of Truth in the Perspective of Counteracting “Bullshit” in the Educational Space of Modern Society

open access: yesФілософія освіти
The article is dedicated to the philosophical analysis of the term “bullshit”, which was systematically conceptualized by the American philosopher Harry G.
Михайло Бойченко   +1 more
doaj   +1 more source

Die Image-Lüge in der Massendemokratie – über einen neuen Typ der politischen Lüge

open access: yesCahiers d’Études Germaniques, 2015
Lies and their consequences can only be pinned down in a specific context of public or private communication. They are relative to the norms and rules of these situations.
Clemens Knobloch
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Un faux mensonge contre un vrai ? Imagination et réalité dans Amoralische Kinderklapper (1969) de Barbara Frischmuth

open access: yesCahiers d’Études Germaniques, 2014
Co-founding Forum Stadtpark (1960), B. Frischmuth struggles against Austrian post-war conservatism based on the myth of a millennial country scarcely influenced by Nazism.
Hélène BARRIÈRE
doaj   +1 more source

The Lie Lie algebra

open access: yes, 2015
Version 3 incorporates several suggestions from the referee. The abstract and introduction have been rewritten to be more user-friendly.
openaire   +2 more sources

Additive Lie (\(\xi \)-Lie) derivations and generalized Lie (\(\xi \)-Lie) derivations on nest algebras

open access: yesLinear Algebra and its Applications, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qi, Xiaofei, Hou, Jinchuan
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Jean-Jacques Rousseau: Literature, politics and the economy of the lie [PDF]

open access: yesFilozofija i Društvo
The following paper seeks to develop - or rather discern - what could be called the politics of literature in Rousseau’s work, by attempting to situate the contradictory nature of the faculty of the imagination in relation to the possibility of ...
Jalagonia Vladimer
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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