Results 61 to 70 of about 468,478 (267)
Splittable Lie Groups and Lie Algebras
Let us call a finite-dimensional Lie algebra \(\mathfrak g\) over a field of characteristic zero Malcev splittable if \(\operatorname {ad}{\mathfrak g}\) is splittable in the sense that for each element of \(\operatorname {ad}{\mathfrak g}\) the semisimple and nilpotent Jordan component belong to \(\operatorname {ad}{\mathfrak g}\).
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The article is dedicated to the philosophical analysis of the term “bullshit”, which was systematically conceptualized by the American philosopher Harry G.
Михайло Бойченко +1 more
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The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
This article uses the game theory, more specifically multiple prisoner’s dilemma game, to analyze why Iranians refused to give up on receiving public subsidies in April 2014, in spite of frequent requests of the government.
Mohammad Reza Javadi Yeganeh
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Version 3 incorporates several suggestions from the referee. The abstract and introduction have been rewritten to be more user-friendly.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qi, Xiaofei, Hou, Jinchuan
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