Results 61 to 70 of about 4,539,711 (302)

Lie Markov models

open access: yesJournal of Theoretical Biology, 2012
Recent work has discussed the importance of multiplicative closure for the Markov models used in phylogenetics. For continuous-time Markov chains, a sufficient condition for multiplicative closure of a model class is ensured by demanding that the set of rate-matrices belonging to the model class form a Lie algebra.
Sumner, Jeremy   +2 more
openaire   +5 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Symplectic, product and complex structures on 3-Lie algebras

open access: yes, 2017
In this paper, first we introduce the notion of a phase space of a 3-Lie algebra and show that a 3-Lie algebra has a phase space if and only if it is sub-adjacent to a 3-pre-Lie algebra.
Sheng, Yunhe, Tang, Rong
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Integration of semidirect product Lie 2-algebras

open access: yes, 2012
The semidirect product of a Lie algebra and a 2-term representation up to homotopy is a Lie 2-algebra. Such Lie 2-algebras include many examples arising from the Courant algebroid appearing in generalized complex geometry.
Sheng, Yunhe, Zhu, Chenchang
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

From Loop Groups to 2-Groups [PDF]

open access: yes, 2005
We describe an interesting relation between Lie 2-algebras, the Kac-Moody central extensions of loop groups, and the group String(n). A Lie 2-algebra is a categorified version of a Lie algebra where the Jacobi identity holds up to a natural isomorphism ...
Baez, John C.   +3 more
core   +2 more sources

Universal Enveloping Algebras of Lie Antialgebras

open access: yes, 2010
Lie antialgebras is a class of supercommutative algebras recently appeared in symplectic geometry. We define the notion of enveloping algebra of a Lie antialgebra and study its properties.
Leidwanger, Séverine   +1 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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