Results 81 to 90 of about 2,091,008 (324)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Horn problem for quasi-hermitian Lie groups [PDF]
, 2020 Paul-Émile Paradan, Paul-Émile Paradan
openalex +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Stability problems and numerical integration on the Lie group SO(3) × R3 × R3
Open Mathematics, 2018 The paper is dealing with stability problems for a nonlinear system on the Lie group SO(3) × R3 × R3. The approximate analytic solutions of the considered system via Optimal Homotopy Asymptotic Method are presented, too.
Pop Camelia, Ene Remus-Daniel
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
A class of 3-dimensional almost Kenmotsu manifolds with harmonic curvature tensors
Open Mathematics, 2016 Let M3 be a three-dimensional almost Kenmotsu manifold satisfying ▽ξh = 0. In this paper, we prove that the curvature tensor of M3 is harmonic if and only if M3 is locally isometric to either the hyperbolic space ℍ3(-1) or the Riemannian product ℍ2(−4) ×
Wang Yaning
doaj +1 more source
Dirac Lie groups, Dirac homogeneous spaces and the Theorem of Drinfeld
, 2011 The notions of \emph{Poisson Lie group} and \emph{Poisson homogeneous space} are extended to the Dirac category. The theorem of Drinfel$'$d (\cite{Drinfeld93}) on the one-to-one correspondence between Poisson homogeneous spaces of a Poisson Lie group and
Jotz, Madeleine
core
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Explicit Parameterizations of Ortho-Symplectic Matrices in
MathematicsStarting from the very first principles we derive explicit parameterizations of the ortho-symplectic matrices in the real four-dimensional Euclidean space.
Clementina D. Mladenova +1 more
doaj +1 more source
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source