Results 81 to 90 of about 2,088,433 (326)

Lorentzian Flat Lie Groups Admitting a Timelike Left-Invariant Killing Vector Field [PDF]

open access: yes, 2013
We call a connected Lie group endowed with a left-invariant Lorentzian flat metric Lorentzian flat Lie group. In this Note, we determine all Lorentzian flat Lie groups admitting a timelike left-invariant Killing vector field.
Lebzioui, Hicham
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Explicit Parameterizations of Ortho-Symplectic Matrices in R4

open access: yesMathematics
Starting from the very first principles we derive explicit parameterizations of the ortho-symplectic matrices in the real four-dimensional Euclidean space.
Clementina D. Mladenova   +1 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Stability problems and numerical integration on the Lie group SO(3) × R3 × R3

open access: yesOpen Mathematics, 2018
The paper is dealing with stability problems for a nonlinear system on the Lie group SO(3) × R3 × R3. The approximate analytic solutions of the considered system via Optimal Homotopy Asymptotic Method are presented, too.
Pop Camelia, Ene Remus-Daniel
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

A class of 3-dimensional almost Kenmotsu manifolds with harmonic curvature tensors

open access: yesOpen Mathematics, 2016
Let M3 be a three-dimensional almost Kenmotsu manifold satisfying ▽ξh = 0. In this paper, we prove that the curvature tensor of M3 is harmonic if and only if M3 is locally isometric to either the hyperbolic space ℍ3(-1) or the Riemannian product ℍ2(−4) ×
Wang Yaning
doaj   +1 more source

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