Results 81 to 90 of about 226,577 (268)

Infinite-Dimensional Lie Groups and Algebras in Mathematical Physics

open access: yesAdvances in Mathematical Physics, 2010
We give a review of infinite-dimensional Lie groups and algebras and show some applications and examples in mathematical physics. This includes diffeomorphism groups and their natural subgroups like volume-preserving and symplectic transformations, as ...
Rudolf Schmid
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Nambu-Lie Groups

open access: yesJournal of Lie Theory, 2000
We extend the Nambu bracket to 1-forms. Following the Poisson-Lie case, we define Nambu-Lie groups as Lie groups endowed with a multiplicative Nambu structure. A Lie group G with a Nambu structure P is a Nambu-Lie group iff P=0 at the unit and the Nambu bracket of left (right) invariant forms is left (right) invariant.
openaire   +3 more sources

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Stacky Lie Groups

open access: yesInternational Mathematics Research Notices, 2008
Presentations of smooth symmetry groups of differentiable stacks are studied within the framework of the weak 2-category of Lie groupoids, smooth principal bibundles, and smooth biequivariant maps. It is shown that principality of bibundles is a categorical property which is sufficient and necessary for the existence of products.
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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