Results 81 to 90 of about 6,154,040 (243)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The theorem of Lie and hyperplane subalgebras of Lie algebras [PDF]
, 1992 Poguntke D. The theorem of Lie and hyperplane subalgebras of Lie algebras. Geometriae Dedicata.
Poguntke, Detlev
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Dynamical equations of multibody systems on Lie groups
Advances in Mechanical Engineering, 2015 The Euler–Poinaré principle is a reduced Hamilton’s principle under Lie group framework. In this article, it is applied to derive a hybrid set of dynamical equations of rigid multibody systems, which include four parts: the classical Euler–Lagrange ...
Wenjie Yu, Zhenkuan Pan
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
DronesThe nonlinear nature of quadrotor dynamics requires high-fidelity reconstruction of vehicle position and attitude. In order to mitigate singularities associated with global three-parameter representations—such as Euler angles—the quadrotor attitude is ...
Zdravko Terze +3 more
doaj +1 more source
On the Homomorphisms of the Lie Groups and
Abstract and Applied Analysis, 2013 We first construct all the homomorphisms from the Heisenberg group to the 3-sphere. Also, defining a topology on these homomorphisms, we regard the set of these homomorphisms as a topological space.
Fatma Özdemir, Hasan Özekes
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Pro-Lie Groups: A Survey with Open Problems
Axioms, 2015 A topological group is called a pro-Lie group if it is isomorphic to a closed subgroup of a product of finite-dimensional real Lie groups. This class of groups is closed under the formation of arbitrary products and closed subgroups and forms a complete ...
Karl H. Hofmann, Sidney A. Morris
doaj +1 more source