Results 71 to 80 of about 226,577 (268)
The Pilgerschritt (Liedl) transform
ESAIM: Proceedings and Surveys, 2014 The Pilgerschritt transform was introduced by Roman Liedl, Innsbruck, in the late seventies of the last century. He came up with the idea for this transform after studies of the Volterra product integral and dealing with questions in ...
Förg-Rob Wolfgang
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
, 2018 In this survey we discuss a wide variety of aspects related to Lie group integrators. These numerical integration schemes for differential equations on manifolds have been studied in a general and systematic manner since the 1990s and the activity has since then branched out in several different subareas, focussing both on theoretical and practical ...
openaire +2 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Pseudoconvexity and Steinness of Connected Complex Lie Groups: A Concise Lie-Theoretic Approach
GeometryWe give new concise Lie-theoretic proofs of basic analytic–geometric properties of connected complex Lie groups. Using Matsushima’s biholomorphic splitting G≃Cn×K˜ together with a refined analysis of the center via its Cousin factor, we show that every ...
Abdel Rahman Al-Abdallah
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FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Dynamical equations of multibody systems on Lie groups
Advances in Mechanical Engineering, 2015 The Euler–Poinaré principle is a reduced Hamilton’s principle under Lie group framework. In this article, it is applied to derive a hybrid set of dynamical equations of rigid multibody systems, which include four parts: the classical Euler–Lagrange ...
Wenjie Yu, Zhenkuan Pan
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Pro-Lie Groups: A Survey with Open Problems
Axioms, 2015 A topological group is called a pro-Lie group if it is isomorphic to a closed subgroup of a product of finite-dimensional real Lie groups. This class of groups is closed under the formation of arbitrary products and closed subgroups and forms a complete ...
Karl H. Hofmann, Sidney A. Morris
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source