Results 41 to 50 of about 470,840 (277)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Lie Ideals in Operator Algebras
, 2002 Let $\mathcal A$ be a Banach algebra for which the group of invertible elements is connected. A subspace $\mathcal L \subseteq \mathcal A$ is a Lie ideal in $\mathcal A$ if, and only if, it is invariant under inner automorphisms. This applies, in particular, to any canonical subalgebra of an AF \ensuremath{\text{C}^{*}}-algebra.
Hopenwasser, Alan, Paulsen, Vern
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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Lie Ideals and Homoderivations in Semiprime Rings
MathematicsLet S be a 2-torsion free semiprime ring and U be a noncentral square-closed Lie ideal of S. An additive mapping ℏ on S is defined as a homoderivation if ℏ(ab)=ℏ(a)ℏ(b)+ℏ(a)b+aℏ(a) for all a,b∈S. In the present paper, we shall prove that ℏ is a commuting
Ali Yahya Hummdi +4 more
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FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
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The Structure of Primitive Leibniz Algebras via Maximal Subalgebras
MathematicsIn this paper, we investigate the structure of primitive Leibniz algebras via their maximal subalgebras and minimal ideals. Using a two-sided definition of the centraliser, we show that the centraliser of a minimal ideal is again an ideal. Unlike the Lie
Zekiye Çiloğlu Şahin
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On generalized Lie derivations of Lie ideals of prime algebras
Linear Algebra and its Applications, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Liao, Ping-Bao, Liu, Cheng-Kai
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
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