Results 51 to 60 of about 14,717 (264)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
La «culture de l'assemblée» dans le 15M
Swiss Journal of Sociocultural AnthropologyEn Espagne, le mouvement du 15M s’est organisé en assemblées autogérées sur les places publiques, dépassant les cercles militants auxquels ces pratiques étaient jusque-là confinées.
Héloïse Nez
doaj +1 more source
STANESCU'S LYRICS IN THE CREATION OF COMPOSERS CORNEL ȚĂRANU AND DAN VOICULESCU [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2020 The article is dedicated to the analysis of cycles of lieds written by Cornel Țăranu and Dan Voiculescu, two remarkable representatives of the Romanian composition school, on the lyrics of Nichita Stănescu. The author focuses on the compositional aspects,
GAMURARI, PAVEL
doaj
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Música Oral del Sur, 2019 El presente artículo gira en torno a la musicalización de las rimas de G. A. Bécquer en el género de la canción lírica, fenómeno desarrollado desde el último tercio del siglo XIX hasta nuestros días.
Candela Tormo Valpuesta
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Temps d'Educació, 2012 Poesia i música, ja des dels seus orígens, han estat estretament relacionades. Aquest article n’explora els diferents nivells d’intertextualitat i la seva aplicació didàctica.
Júlia Ferrer i Garcia +1 more
doaj
Hum, 2009 Es ist die Rede von einer durch die Schönheit der Heimatslandschaft motivierenden Poesie wie überhaupt die Schönheit des Kosmos betreffend oder der Natur im Ganzen, in der „Logos, und nicht Kaos“ herrscht.
Šimun Musa
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source